CIR1 Antibody
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中文名稱：CIR1兔多克隆抗體
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貨號：CSB-PA773051DSR2HU
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規格：￥440
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圖片：
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Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA773051DSR2HU at dilution of 1:100 -
Immunohistochemistry of paraffin-embedded human endometrial cancer using CSB-PA773051DSR2HU at dilution of 1:100
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) CIR1 Polyclonal antibody
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Uniprot No.：
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基因名：
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別名：CIR1 antibody; CIRCorepressor interacting with RBPJ 1 antibody; CBF1-interacting corepressor antibody; Recepin antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Corepressor interacting with RBPJ 1 protein (1-160AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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產品提供形式：Liquid
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應用范圍：ELISA, IHC
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推薦稀釋比：
Application Recommended Dilution IHC 1:20-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：May modulate splice site selection during alternative splicing of pre-mRNAs. Regulates transcription and acts as corepressor for RBPJ. Recruits RBPJ to the Sin3-histone deacetylase complex (HDAC). Required for RBPJ-mediated repression of transcription.
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基因功能參考文獻：
- three SNPs (corepressor interacting with RBPJ 1 (CIR1) rs13009079T>C, ribonucleotide reductase M1 (RRM1) rs1465952T>C and solute carrier family 38, member 4 (SLC38A4) rs2429467C>T), may play a role in the pathogenesis of lung cancer PMID: 27587543
- identified as a PAP-1 binding protein and as a splicing factor PMID: 15652350
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亞細胞定位：Nucleus speckle. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Colocalizes with NEK6 in the centrosome.
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組織特異性：Highly expressed in heart, brain, placenta, liver, skeletal muscle and pancreas.
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數據庫鏈接：
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