CHAD Antibody, Biotin conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) CHAD Polyclonal antibody
Uniprot No.：

O15335
基因名：

CHAD
別名：

Cartilage leucine rich protein antibody; Cartilage leucine-rich protein antibody; Chad antibody; CHAD_HUMAN antibody; Chondroadherin antibody; Chondroadherin proteoglycan antibody; SLRR4A antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Chondroadherin protein (23-359AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Promotes attachment of chondrocytes, fibroblasts, and osteoblasts. This binding is mediated (at least for chondrocytes and fibroblasts) by the integrin alpha(2)beta(1). May play an important role in the regulation of chondrocyte growth and proliferation.
基因功能參考文獻：
1. crystal structures at ~2.2A resolution of human fibromodulin and chondroadherin. PMID: 28215822
2. number of cells adhering via their beta(1) integrin receptor to collagen type II or chondroadherin was profoundly and rapidly enhanced by the addition of the heparin-binding peptide PMID: 23172228
3. chondroadherin interaction with cells may be central for maintaining the adult chondrocyte phenotype and cartilage homeostasis. PMID: 21127050
4. Changes in CHAD abundance or structure could be associated with the pathologic changes occurring in the scoliotic IVD. PMID: 19525844
亞細胞定位：

Secreted, extracellular space, extracellular matrix.
蛋白家族：

Small leucine-rich proteoglycan (SLRP) family, SLRP class IV subfamily
組織特異性：

Present in chondrocytes at all ages.
數據庫鏈接：

HGNC: 1909

OMIM: 602178

KEGG: hsa:1101

STRING: 9606.ENSP00000258969

UniGene: Hs.97220

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