CGA Antibody
-
中文名稱：CGA兔多克隆抗體
-
貨號：CSB-PA131153
-
規格：￥1100
-
圖片：
-
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA131153(CGA Antibody) at dilution 1/65, on the right is treated with fusion protein. (Original magnification: ×200)
-
-
其他：
產品詳情
-
Uniprot No.：
-
基因名：
-
別名：Anterior pituitary glycoprotein hormones common subunit alpha antibody; CG alpha antibody; CG-alpha antibody; cga antibody; Choriogonadotropin alpha chain antibody; Chorionic Gonadotrophin Alpha antibody; Chorionic Gonadotrophin Alpha Subunit antibody; Chorionic gonadotrophin subunit alpha antibody; chorionic gonadotropin, alpha polypeptide antibody; Follicle-stimulating hormone alpha antibody; Follicle-stimulating hormone alpha chain antibody; follicle-stimulating hormone alpha subunit antibody; Follitropin alpha antibody; Follitropin alpha chain antibody; FSH Alpha antibody; FSH-alpha antibody; FSHA antibody; GLHA_HUMAN antibody; Glycoprotein hormones alpha chain antibody; Glycoprotein Hormones Alpha Polypeptide antibody; GPH Alpha antibody; GPHa antibody; GPHA1 antibody; HCG antibody; hyrotropin alpha antibody; LH-alpha antibody; LHA antibody; LSH alpha antibody; LSH-alpha antibody; Luteinizing hormone alpha antibody; Luteinizing hormone alpha chain antibody; Lutropin alpha antibody; Lutropin alpha chain antibody; Thyroid Stimulating Hormone Alpha antibody; Thyroid Stimulating Hormone Alpha Chain antibody; Thyroid-stimulating hormone alpha chain antibody; Thyrotropin alpha chain antibody; TSH Alpha antibody; TSH-alpha antibody; TSHA antibody
-
宿主：Rabbit
-
反應種屬：Human
-
免疫原：Fusion protein of Human CGA
-
免疫原種屬：Homo sapiens (Human)
-
標記方式：Non-conjugated
-
抗體亞型：IgG
-
純化方式：Antigen affinity purification
-
濃度：It differs from different batches. Please contact us to confirm it.
-
保存緩沖液：-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
-
產品提供形式：Liquid
-
應用范圍：ELISA,IHC
-
推薦稀釋比：
Application Recommended Dilution ELISA 1:2000-1:5000 IHC 1:50-1:200 -
Protocols：
-
儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
-
用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
-
功能：Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways.
-
基因功能參考文獻：
- This study which performed for the first time in Iran suggests that polymorphism in CGA gene can affect male infertility. PMID: 29627965
- Our findings support a model in which CREB3L1 acts as a downstream effector of TSH to regulate the expression of cargo proteins, and simultaneously increases the synthesis of transport factors and the expansion of the Golgi to synchronize the rise in cargo load with the amplified capacity of the secretory pathway PMID: 29093023
- men with higher and women with lower serum TSH levels are at increased risk of frailty. PMID: 27869535
- Inhibin-B secretion and FSH isoform distribution may play an integral part of follicular selection in the natural menstrual cycle. (Review) PMID: 27756855
- proteomic study reveals unique protein changes in both cellular (98% unique identifications) and secreted (96% unique identifications) proteins in the transition to the progesterone-dominated secretory (receptive) phase and subsequently to pregnancy, mediated by embryo-derived human chorionic gonadotropin (hCG) PMID: 27262222
- the in vivo bioactivities of FSH glycoforms in Fshb null mice using a pharmacological rescue approach, was investigated. PMID: 27561202
- In girls with central precocious puberty, increased body mass index (BMI) was associated with slightly lower peak stimulated luteinizing hormone (LH) levels at early pubertal stages (Tanner stages 2 and 3). PMID: 27215137
- the distribution of 1(st) trimester TSH and evaluate its association with perinatal outcomes and future development of maternal thyrotoxicosis, is reported. PMID: 27351808
- The present results have for the first time shown protective effects exerted by hCG on vascular endothelial function. PMID: 26279419
- Human chorionic gonadotropin provides a mechanism to bridge embryo to endometrium through beta1,4-GalT. PMID: 26191157
- thyroid-stimulating hormone elevations can obviously be the initial finding in pseudohypoparathyroidism type Ib patients. PMID: 25403028
- TBP attenuates Msx1-mediated glycoprotein hormone alpha transcriptional repression. PMID: 26505791
- The results indicate that gal-3 might be regulated by Human chorionic gonadotropin (hCG)in preparing the endometrium for embryonic implantation. PMID: 21705042
- Limitations in the process of transcription and translation inhibit recombinant human chorionic gonadotropin expression in CHO cells. PMID: 25529346
- the 5-aminoimidazole-4-carboxyamide ribonucleoside (AICAR)-induced activation of AMPK directly inhibited the expression of SREBP-2 and HMGCR and HMGCS, and suppressed the TSH-stimulated up-regulation of SREBP-2 in HepG2 cells. PMID: 25933205
- Serum TSH was associated with pulse wave velocity on population level when adjusted with age and sex. PMID: 25185682
- A single low TSH at baseline was associated with increased risk of hip fractures (adj HR 1.16, 95% CI 1.07-1.26, p < 0.001) but not major osteoporotic fractures (MOF, adj HR 1.06, 95% CI 0.99-1.12, p = 0.058) over a median follow-up of 7.5 years. PMID: 24723381
- This study showed a link between low maternal serum hCG levels and cryptorchidism in boys from uncomplicated pregnancy. PMID: 25064170
- A protective effect of hCG against breast cancer may be associated with its growth inhibitory and differentiation induction function in breast cancer cells. PMID: 24753159
- LH, progesterone, and TSH can stimulate aldosterone. PMID: 24297486
- Elevated total hCG and free beta-hCG concentrations during early pregnancy are associated with nonstatistically significant reductions in maternal risk of breast cancer. PMID: 24559445
- chromogranin A PMID: 23153859
- The purpose of these studies was to determine if CTNNB1's contribution to FSH-mediated steroidogenesis in primary rat granulosa cells was due in part to extracellular stimulation of the canonical WNT signaling pathway. PMID: 24466091
- Hypo-glycosylated human follicle-stimulating hormone is much more active in vitro than its fully-glycosylated counterpart. PMID: 24291635
- New information about TSH signaling in human differentiated adipocytes, and add to the evidence that TSH is a pro-inflammatory stimulus of adipocytes. PMID: 24661543
- Human chorionic gonadotropin hormone stimulates trophoblast invasion independently of the hCG receptor. PMID: 23684886
- data further identified a complex interaction between IL1 and hCG, which, despite a synergistic action on several significant endometrial target genes, may encompass a tight control of endogenous IL1 and extends to other IL1 family members PMID: 23717664
- Msx1 functions as a negative regulator early in pituitary development by repressing the gonadotrope-specific alphaGSU and GnRHR genes. PMID: 23371388
- BK(Ca) is a crucial part of the signaling cascade of LH/hCG in Leydig cells. PMID: 23267835
- In our multi-ethnic cohort of euthyroid obese children and adolescents increasing TSH was associated with impaired glucose metabolism and dyslipidemia. PMID: 23525871
- Data indicate that neither serum inhibin B nor follicle-stimulating hormone (FSH) is a suitable surrogate for determination of sperm concentration in a semen sample. PMID: 23423746
- Ser680 genotype for FSHR is a factor of relative resistance to FSH stimulation resulting in slightly higher FSH serum levels, thus leading to a prolonged duration of the menstrual cycle. PMID: 23380184
- The use of these age-specific reference intervals for TSH, especially in those over 70 years old, would result in the reclassification of many TSH results from "abnormal" to "normal" and avoid unnecessary treatment. PMID: 23345094
- hCG coordinates embryonic signal interaction with the maternal endometrium and may promote embryonic growth. PMID: 22811570
- N-acetyl-L-cysteine modulates multiple signaling pathways to rescue male germ cells from apoptosis induced by chorionic gonadotropin. PMID: 22354444
- Data suggest that in embryonic stem cells [which express proto-oncogene c-ETS-2 (ETS2) but not CGA], ETS2 does not occupy its binding site on CGA promoter but is found instead as soluble complex with POU5F1 (Oct3 transcription factor). PMID: 22446105
- low urinary level of hyperglycosylated hCG is associated with pregnancy failure PMID: 22386126
- second-trimester maternal serum levels of alpha-fetoprotein, human chorionic gonadotropin, and unconjugated estriol may have a role in bronchopulmonary dysplasia PMID: 22391642
- Data suggest that a progressive increase in TSH are predictive factors for thyroid failure in Hashimoto's thyroiditis (HT) patients. PMID: 21981142
- Data suggest that likelihood of papillary thyroid carcinoma is reduced when serum TSH is lower, as in thyroid autonomy, and increased when serum TSH is higher, as in thyroid autoimmunity. [Meta-Analysis; REVIEW] PMID: 22278420
- TSH showed significant positive correlation with creatinine and uric acid values and, thyroid function test had a negative correlation with uric acid in overt hypothyroidism. PMID: 22061337
- Serum IL-6, IL-1beta and hCG levels were significantly increased in women with pre-eclampsia compared to controls. PMID: 21623995
- TSH-TSHR interaction through cAMP signaling (using thyrogen/rTSHalpha) is involved in differentiation/gene expression regulation of bone marrow-derived mesenchymal stem cells; first evidence of expression of TSHR in stem cell plasma membrane. PMID: 22128326
- investigation of hCG in seminal plasma: Level of free hCGa is reduced in infertility with abnormal semen analysis. In oligospermia, holo-hCG is low; hCGa is present as highly glycosylated large free subunit with a unique glycosylation pattern. PMID: 21838882
- TSH is a novel neuroendocrine regulator of selected keratins in the human hair follicle PMID: 21763112
- Increasing concentrations of FSH caused a biphasic dose-response, with a maximal (1.5-fold) increase in RANK(high) cells. PMID: 21159522
- In euthyroid children without a history of hypo- or hyperthyroidism, increasing levels of TSH and decreasing levels of free T4 are associated with higher triglyceride levels and elevated markers of insulin resistance. PMID: 21114382
- Results suggest that a serum TSH concentration at the lower end of the reference range may be associated with low BMD in men. PMID: 20455884
- Findings demonstrate that FSH has dose-dependent anabolic effects on bone via an ovary-dependent mechanism. PMID: 21149714
- Women with high TSH at end term are at risk for breech presentation. Substantial evidence for a relation between breech presentation and neurodevelopmental delay exists. PMID: 20718770
顯示更多
收起更多
-
亞細胞定位：Secreted.
-
蛋白家族：Glycoprotein hormones subunit alpha family
-
數據庫鏈接：
Most popular with customers
-
-
YWHAB Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC, IF, FC
Species Reactivity: Human, Mouse, Rat
-
Phospho-YAP1 (S127) Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC
Species Reactivity: Human
-
-
-
-
-
