CEACAM16 Antibody, FITC conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) CEACAM16 Polyclonal antibody
Uniprot No.：

Q2WEN9
基因名：

CEACAM16
別名：

CEACAM16 antibody; CEAL2Carcinoembryonic antigen-related cell adhesion molecule 16 antibody; Carcinoembryonic antigen-like 2 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Carcinoembryonic antigen-related cell adhesion molecule 16 protein (323-414AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

FITC
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Required for proper hearing, plays a role in maintaining the integrity of the tectorial membrane.
基因功能參考文獻：
1. Results confirm that CEACAM6 promoted cell proliferation mediated by cyclin D1/CDK4. PMID: 26497080
2. Data indicate that a heterozygous missense mutation, c.505G>A (p.G169R) in exon 3 of the CEACAM16 gene (carcinoembryonic antigen-related cell adhesion molecule 16) was identified in autosomal dominant nonsyndromic hearing loss family. PMID: 25589040
3. CEACAM16 can probably form higher order structures with other tectorial membrane proteins such as alpha-tectorin and beta-tectorin and influences the physical properties of the tectorial membrane PMID: 22544735
4. data identify CEACAM16 as an alpha-tectorin-interacting protein that concentrates at the point of attachment of the TM to the stereocilia and, when mutated, results in ADNSHL at the DFNA4 locus PMID: 21368133
相關疾病：

Deafness, autosomal dominant, 4B (DFNA4B)
亞細胞定位：

Secreted.
蛋白家族：

Immunoglobulin superfamily, CEA family
數據庫鏈接：

HGNC: 31948

OMIM: 614591

KEGG: hsa:388551

STRING: 9606.ENSP00000385576

UniGene: Hs.456381

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