CDC42EP2 Antibody

說(shuō)明書(shū)

中文名稱：

CDC42EP2兔多克隆抗體
貨號(hào)：

CSB-PA005013LA01HU
規(guī)格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA005013LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA005013LA01HU at dilution of 1:100
其他：

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) CDC42EP2 Polyclonal antibody
Uniprot No.：

O14613
基因名：

CDC42EP2
別名：

Binder of Rho GTPases 1 antibody; BORG1 antibody; BORG1_HUMAN antibody; CDC42 effector protein (Rho GTPase binding) 2 antibody; Cdc42 effector protein 2 antibody; Cdc42ep2 antibody; CEP2 antibody; CRIB-containing BOGR1 protein antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Recombinant Human Cdc42 effector protein 2 protein (9-210AA)
免疫原種屬：

Homo sapiens (Human)

標(biāo)記方式：

Non-conjugated

本頁(yè)面中的產(chǎn)品，CDC42EP2 Antibody (CSB-PA005013LA01HU)，的標(biāo)記方式是Non-conjugated。對(duì)于CDC42EP2 Antibody，我們還提供其他標(biāo)記。見(jiàn)下表：

標(biāo)記方式	貨號(hào)	產(chǎn)品名稱	應(yīng)用
HRP	CSB-PA005013LB01HU	CDC42EP2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA005013LC01HU	CDC42EP2 Antibody, FITC conjugated
Biotin	CSB-PA005013LD01HU	CDC42EP2 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts in a CDC42-dependent manner.
基因功能參考文獻(xiàn)：
1. Studies indicate some of the functional and mechanistic roles of the binder of Rho GTPases Borg1-5 proteins (Cdc42EP1-5), including cytoskeletal remodelling and signalling. PMID: 27913681
2. CDC42EP2 is upregulated in human PDLCs subjected to tensile stress related to mechano-induced cell cycle arrest. PMID: 20934684
3. activations of Rac1 and Cdc42 are involved in the hypoxia-induced production of angiogenesis-promoting factors and tumor suppressors, and suggest that the Rho family GTPases Rac1 and Cdc42 may contribute to the hypoxia-mediated angiogenesis. PMID: 16395716
亞細(xì)胞定位：

Endomembrane system; Peripheral membrane protein. Cytoplasm, cytoskeleton.
蛋白家族：

BORG/CEP family
組織特異性：

Highly expressed in the heart. Weakly expressed in the pancreas and liver.
數(shù)據(jù)庫(kù)鏈接：

HGNC: 16263

OMIM: 606132

KEGG: hsa:10435

STRING: 9606.ENSP00000279249

UniGene: Hs.343380

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