CCT6A Antibody
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中文名稱：CCT6A兔多克隆抗體
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貨號：CSB-PA004865ESR1HU
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規格：￥440
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圖片：
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Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA004865ESR1HU at dilution of 1:100 -
Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA004865ESR1HU at dilution of 1:100 -
Immunoprecipitating CCT6A in Hela whole cell lysate
Lane 1: Rabbit control IgG instead of CSB-PA004865ESR1HU in Hela whole cell lysate. For western blotting, a HRP-conjugated Protein G antibody was used as the secondary antibody (1/2000)
Lane 2: CSB-PA004865ESR1HU (8μg) + Hela whole cell lysate (500μg)
Lane 3: Hela whole cell lysate (10μg)
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) CCT6A Polyclonal antibody
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Uniprot No.：
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基因名：CCT6A
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別名：CCT6A antibody; CCT6 antibody; CCTZ antibody; T-complex protein 1 subunit zeta antibody; TCP-1-zeta antibody; Acute morphine dependence-related protein 2 antibody; CCT-zeta-1 antibody; HTR3 antibody; Tcp20 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human T-complex protein 1 subunit zeta protein (80-250AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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產品提供形式：Liquid
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應用范圍：ELISA, IHC, IP
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推薦稀釋比：
Application Recommended Dilution IHC 1:20-1:200 IP 1:200-1:2000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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靶點詳情
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功能：Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. The TRiC complex plays a role in the folding of actin and tubulin (Probable).
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基因功能參考文獻：
- High expression of CCT6A is associated with Non-Small Cell Lung Cancer. PMID: 28104536
- selective inhibition of SMAD3 or CCT6A efficiently suppresses TGF-beta-mediated metastasis. Findings provide a mechanism that directs TGF-beta signaling toward its prometastatic arm and may contribute to the development of therapeutic strategies targeting TGF-beta for non-small-cell lung carcinoma. PMID: 28375158
- These data suggest that CCT6A is a novel autoantigen recognized by Vdelta2 gammadelta T cells, which deepens our understanding of mechanisms in autoimmune diseases. PMID: 27489109
- identified genes, which include Tcp20, may play important role in conferring radioresistance to oral squamous cell carcinoma and could be useful in identifying cases with more radioresistance PMID: 16211299
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亞細胞定位：Cytoplasm.
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蛋白家族：TCP-1 chaperonin family
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數據庫鏈接：
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