CCT2 Antibody
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中文名稱：CCT2兔多克隆抗體
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貨號(hào)：CSB-PA004856ESR1HU
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規(guī)格：￥440
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圖片：
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Western blot
All lanes: CCT2 antibody at 5.63μg/ml
Lane 1: Jurkat whole cell lysate
Lane 2: NIH/3T3 whole cell lysate
Lane 3: MCF-7 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 58, 53 kDa
Observed band size: 58 kDa -
Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA004856ESR1HU at dilution of 1:100 -
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA004856ESR1HU at dilution of 1:100 -
Immunoprecipitating CCT2 in Jurkat whole cell lysate
Lane 1: Rabbit control IgG instead of (1μg) instead of CSB-PA004856ESR1HU in Jurkat whole cell lysate. For western blotting, a HRP-conjugated light chain specific antibody was used as the Secondary antibody (1/50000)
Lane 2: CSB-PA004856ESR1HU (4μg) + Jurkat whole cell lysate (500μg)
Lane 3: Jurkat whole cell lysate (20μg)
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) CCT2 Polyclonal antibody
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Uniprot No.：
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基因名：
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別名：99D8.1 antibody; CCT 2 antibody; CCT beta antibody; CCT-beta antibody; CCT2 antibody; CCTB antibody; Chaperonin containing t complex polypeptide 1 beta subunit antibody; Chaperonin containing t complex polypeptide 1 subunit 2 antibody; Chaperonin containing TCP1 subunit 2 antibody; Chaperonin containing TCP1 subunit 2 (beta) antibody; CTP:phosphocholine cytidylyltransferase 2 antibody; Epididymis secretory sperm binding protein Li 100n antibody; HEL S 100n antibody; MGC142074 antibody; MGC142076 antibody; MGC94480 antibody; PRO1633 antibody; T complex protein 1 beta subunit antibody; T complex protein 1 subunit beta antibody; T-complex protein 1 subunit beta antibody; TCP 1 beta antibody; TCP-1-beta antibody; TCPB_HUMAN antibody
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宿主：Rabbit
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反應(yīng)種屬：Human
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免疫原：Recombinant Human T-complex protein 1 subunit beta protein (206-535AA)
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：Non-conjugated
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA, WB, IHC, IP
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推薦稀釋比：
Application Recommended Dilution WB 1:1000-1:5000 IHC 1:20-1:200 IP 1:200-1:2000 -
Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. The TRiC complex plays a role in the folding of actin and tubulin.
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基因功能參考文獻(xiàn)：
- the novel LCA mutations in CCTbeta and the impact of chaperon disability by these mutations in cellular biology. PMID: 27645772
- A role for the TRiC subunits TCP1 and CCT2, and potentially the entire TRiC complex, in breast cancer. PMID: 25704758
- Increased expression of CCT2 is associated with tumor progression and the clinical behavior of gallbladder carcinoma. PMID: 23782473
- PDCD5 bound the apical domain of the CCTbeta subunit, projecting above the folding cavity without entering it. Like PDCD5, beta-tubulin also interacts with the CCTbeta apical domain, but a second site is found at the sensor loop deep within the folding cavity. PMID: 24375412
- PB2 associates with CCT2 as a monomer and the CCT binding site is located in a central region of the PB2 protein. PMID: 20573828
- The chaperonin CCT is identified as a novel physiological substrate for p90 ribosomal S6 kinase (RSK) and p70 ribosomal S6 kinase (S6K). PMID: 19332537
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亞細(xì)胞定位：Cytoplasm.
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蛋白家族：TCP-1 chaperonin family
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數(shù)據(jù)庫鏈接：
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