CBR4 Antibody
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中文名稱：CBR4兔多克隆抗體
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貨號(hào)：CSB-PA850803ESR1HU
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規(guī)格：￥440
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圖片：
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Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA850803ESR1HU at dilution of 1:100 -
Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA850803ESR1HU at dilution of 1:100
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) CBR4 Polyclonal antibody
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Uniprot No.：
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基因名：CBR4
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別名：3 oxoacyl [acyl carrier protein] reductase antibody; 3-oxoacyl-[acyl-carrier-protein] reductase antibody; Carbonic reductase 4 antibody; Carbonyl reductase 4 antibody; Carbonyl reductase family member 4 antibody; CBR 4 antibody; Cbr4 antibody; CBR4_HUMAN antibody; FLJ14431 antibody; Quinone reductase CBR4 antibody; SDR45C1 antibody; Short chain dehydrogenase/reductase family 45C member 1 antibody
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宿主：Rabbit
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反應(yīng)種屬：Human
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免疫原：Recombinant Human Carbonyl reductase family member 4 protein (1-237AA)
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：Non-conjugated
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克隆類(lèi)型：Polyclonal
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA, IHC
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推薦稀釋比：
Application Recommended Dilution IHC 1:20-1:200 -
Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Component of the heterotetramer complex KAR (3-ketoacyl-[acyl carrier protein] reductase or 3-ketoacyl-[ACP] reductase) that forms part of the mitochondrial fatty acid synthase (mtFAS). Beta-subunit of the KAR heterotetramer complex, responsible for the 3-ketoacyl-ACP reductase activity of the mtFAS, reduces 3-oxoacyl-[ACP] to (3R)-hydroxyacyl-[ACP] in a NADPH-dependent manner with no chain length preference, thereby participating in mitochondrial fatty acid biosynthesis. The homotetramer has NADPH-dependent quinone reductase activity (in vitro), hence could play a role in protection against cytotoxicity of exogenous quinones. As a heterotetramer, it can also reduce 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o-quinones and p-quinones (in vitro).
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基因功能參考文獻(xiàn)：
- CBR4 is a mitochondrial NADPH-dependent reductase for o- and p-quinones. PMID: 19000905
- Hs17beta-HSD8 and HsCBR4 show a strong genetic interaction in vivo in yeast, where, only if they are expressed together, they rescue the respiratory deficiency and restore the lipoic acid content of oar1Delta cells. PMID: 19571038
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亞細(xì)胞定位：Mitochondrion matrix.
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蛋白家族：Short-chain dehydrogenases/reductases (SDR) family
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組織特異性：Detected in liver and kidney (at protein level). Displays the highest expression in neuronal and muscle tissues.
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數(shù)據(jù)庫(kù)鏈接：
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