CARD18 Antibody

中文名稱：

CARD18兔多克隆抗體
貨號：

CSB-PA004521LA01HU
規格：

￥440
圖片：
IHC image of CSB-PA004521LA01HU diluted at 1:100 and staining in paraffin-embedded human heart tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
其他：

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) CARD18 Polyclonal antibody
Uniprot No.：

P57730
基因名：

CARD18
別名：

CARD18 antibody; ICEBERG antibody; UNQ5804/PRO19611Caspase recruitment domain-containing protein 18 antibody; Caspase-1 inhibitor Iceberg antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Caspase recruitment domain-containing protein 18 protein (1-90AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，CARD18 Antibody (CSB-PA004521LA01HU)，的標記方式是Non-conjugated。對于CARD18 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA004521LB01HU	CARD18 Antibody, HRP conjugated	ELISA
FITC	CSB-PA004521LC01HU	CARD18 Antibody, FITC conjugated
Biotin	CSB-PA004521LD01HU	CARD18 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Inhibits generation of IL-1-beta by interacting with caspase-1 and preventing its association with RIP2. Down-regulates the release of IL1B.
基因功能參考文獻：
1. In lesional epidermis of patients with lichen planus, CARD18 expression was either greatly diminished or entirely absent whereas in non-lesional areas expression was comparable to normal skin. PMID: 28506683
2. CARD18 expression differs in healthy and psoriatic skin; moreover, CARD18 demonstrated altered response under inflammatory conditions in healthy and psoriatic skin PMID: 27023378
3. CARD18 may be both a promising marker for prognosis and a target protein for treatment of gastric cancer. PMID: 23948415
組織特異性：

Primarily expressed in the heart and placenta.
數據庫鏈接：

HGNC: 28861

OMIM: 605354

KEGG: hsa:59082

STRING: 9606.ENSP00000436691

UniGene: Hs.56279

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