CAMK2N1 Antibody

中文名稱：

CAMK2N1兔多克隆抗體
貨號：

CSB-PA004469NA01HU
規格：

￥440
圖片：
Immunofluorescence staining of HepG2 cells with CSB-PA004469NA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
其他：

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) CAMK2N1 Polyclonal antibody
Uniprot No.：

Q7Z7J9
基因名：

CAMK2N1
別名：

CAMK2N1Calcium/calmodulin-dependent protein kinase II inhibitor 1 antibody; CaMKII inhibitory protein alpha antibody; CaMKIIN-alpha antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Peptide sequence from Human Calcium/calmodulin-dependent protein kinase II inhibitor 1 protein (9-27AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，CAMK2N1 Antibody (CSB-PA004469NA01HU)，的標記方式是Non-conjugated。對于CAMK2N1 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA004469NB01HU	CAMK2N1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA004469NC01HU	CAMK2N1 Antibody, FITC conjugated
Biotin	CSB-PA004469ND01HU	CAMK2N1 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IF

推薦稀釋比：

Application	Recommended Dilution
IF	1:50-1:200

Protocols：

ELISA Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Potent and specific inhibitor of CaM-kinase II (CAMK2).
基因功能參考文獻：
1. CAMK2N1 expression is significantly downregulated in human masticatory mucosa during wound healing PMID: 28005267
2. Hypermethylation of RUNX3/CAMK2N1 is associated with poor clinical outcome in Type II EOC, also after macroscopic complete resection. PMID: 26175272
3. contributes to prostate cancer growth and survival through androgen receptor-dependent signaling PMID: 25296973
4. Analyses suggest that CAMK2N1 plays a tumor suppressive role in prostate cancer cells. Reduced CAMK2N1 expression correlates to human prostate cancer progression and predicts poor clinical outcome. PMID: 25003983
5. hCaMKIINalpha suppresses tumor growth by inducing cell cycle arrest via p27 stabilization PMID: 18305109
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亞細胞定位：

Cell junction, synapse, synaptosome. Cell junction, synapse, postsynaptic density.
蛋白家族：

CAMK2N family
組織特異性：

Widely expressed. Nor detected in skeletal muscle.
數據庫鏈接：

HGNC: 24190

OMIM: 614986

KEGG: hsa:55450

UniGene: Hs.731383

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