C16orf62 Antibody

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) C16orf62 Polyclonal antibody
Uniprot No.：

Q7Z3J2
基因名：

C16orf62
別名：

C16orf62 antibody; Chromosome 16 open reading frame 62 antibody; CP062_HUMAN antibody; DKFZp313M0539 antibody; DKFZp434B0212 antibody; Esophageal cancer associated protein antibody; Esophageal cancer-associated protein antibody; FLJ21040, antibody; Hypothetical protein LOC57020 antibody; MGC16824 antibody; UPF0505 protein C16orf62 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human UPF0505 protein C16orf62 protein (6-205AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，C16orf62 Antibody (CSB-PA773584HA01HU)，的標記方式是Non-conjugated。對于C16orf62 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA773584HB01HU	C16orf62 Antibody, HRP conjugated	ELISA
FITC	CSB-PA773584HC01HU	C16orf62 Antibody, FITC conjugated
Biotin	CSB-PA773584HD01HU	C16orf62 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, WB, IF

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:5000
IF	1:50-1:200

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Acts as component of the retriever complex. The retriever complex is a heterotrimeric complex related to retromer cargo-selective complex (CSC) and essential for retromer-independent retrieval and recycling of numerous cargos such as integrin alpha-5/beta-1 (ITGA5:ITGB1). The recruitment of the retriever complex to the endosomal membrane involves CCC and WASH complexes. In the endosomes, drives the retrieval and recycling of NxxY-motif-containing cargo proteins by coupling to SNX17, a cargo essential for the homeostatic maintenance of numerous cell surface proteins associated with processes that include cell migration, cell adhesion, nutrient supply and cell signaling. Involved in copper-dependent ATP7A trafficking between the trans-Golgi network and vesicles in the cell periphery; the function is proposed to depend on its association with the CCC complex and cooperation with the WASH complex on early endosomes. Seems not to be required for CCC complex stability.; (Microbial infection) The heterotrimeric retriever complex, in collaboration with the CCC complex, mediates the exit of human papillomavirus to the cell surface.
基因功能參考文獻：
1. Heterotrimer composed of DSCR3, C16orf62 and VPS29 orchestrates endosomal cargo retrieval and recycling. PMID: 28892079
亞細胞定位：

Membrane; Single-pass membrane protein. Endosome.
蛋白家族：

UPF0505 family
數據庫鏈接：

HGNC: 24641

KEGG: hsa:57020

STRING: 9606.ENSP00000400815

UniGene: Hs.654964

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