BMP8B Antibody

說明書

產品詳情

Uniprot No.：

P34820
基因名：

BMP8B
別名：

BMP-8 antibody; BMP-8B antibody; BMP8 antibody; Bmp8b antibody; BMP8B_HUMAN antibody; bone morphogenetic protein 8 (osteogenic protein 2) antibody; Bone morphogenetic protein 8 antibody; Bone morphogenetic protein 8B antibody; dJ118J21.1 (bone morphogenetic protein 8 (osteogenic protein 2)) antibody; OP-2 antibody; OP2 antibody; Osteogenic protein 2 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Synthesized peptide derived from the Internal region of Human BMP-8B.
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
產品提供形式：

Liquid
應用范圍：

WB, ELISA

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:2000
ELISA	1:40000

Protocols：

Western Blotting (WB) Protocol
ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis.
基因功能參考文獻：
1. Acetylated H3K9 and H4K16 levels at BMP8B were increased in gastric cancer (GC) compared to nontumors (P < 0.05). However, reduced levels of acetylated H3K9 and H4K16 were associated with poorly differentiated GC (P < 0.05). PMID: 27748538
2. Study found that BMP8B was downregulated in pancreatic cancer tissues and BMP8B mediates the survival of pancreatic cancer cells and regulates the progression of pancreatic cancer. PMID: 25176058
3. Five novel SNPs within BMP8B gene.Genetic variants in BMP8B gene are associated with growth traits in Chinese native cattle. PMID: 24076131
4. Epigenetic silencing of the bone morphogenetic protein 2 gene through methylation is associated with gastric carcinomas PMID: 16314833
5. Reports on the mouse homolog of this gene. PMID: 9070944
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亞細胞定位：

Secreted.
蛋白家族：

TGF-beta family
數據庫鏈接：

HGNC: 1075

OMIM: 602284

KEGG: hsa:656

STRING: 9606.ENSP00000361915

UniGene: Hs.734367

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