BLLF1 Antibody, HRP conjugated

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說明書

中文名稱：

BLLF1兔多克隆抗體, HRP偶聯
貨號：

CSB-PA360986LB01EFA
規格：

￥880
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

產品名稱：

Rabbit anti-Epstein-Barr virus BLLF1 Polyclonal antibody
Uniprot No.：

P03200
基因名：

BLLF1
別名：

BLLF1 antibody; Envelope glycoprotein GP350 antibody; Membrane antigen antibody; MA antibody
宿主：

Rabbit
反應種屬：

Epstein-Barr virus
免疫原：

Recombinant Epstein-Barr virus Envelope glycoprotein GP350 protein (1-493AA)
免疫原種屬：

Epstein-Barr virus
標記方式：

HRP
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Initiates virion attachment to host B-lymphocyte cell, leading to virus entry. Acts by binding to host CR2 at the surface of B-lymphocytes, facilitating the binding of viral glycoprotein gp42 to HLA class II molecules. Attachment triggers virion-host membrane fusion and invasion of the host cell.
基因功能參考文獻：
1. The similar distribution of gp350/220 variants in nasopharyngeal carcinoma, EBV-associated gastric carcinoma and healthy donors suggest that gp350/220 variations are geographically restricted rather than tumor-specific polymorphisms. PMID: 22038027
2. gp350 mainly exerts its functions after the internalization step, presumably during release of the viral capsid from the endosomal compartment, and that CD21-dependent but also CD21-independent molecular mechanisms are involved in this process. PMID: 19889766
3. X-ray structure of the highly glycosylated gp350; defined the CR2 binding site on gp350, deglycosylated gp350 bound CR2 similarly to the glycosylated form, suggesting that glycosylation is not important for receptor binding PMID: 17072314
4. These site-directed mutations identified a novel negatively charged complement receptor type 2-binding surface described by residues Glu-21, Asp-22, Glu-155, Asp-208, Glu-210, and Asp-296. PMID: 18786993
亞細胞定位：

Virion membrane; Single-pass membrane protein. Host membrane; Single-pass membrane protein. Note=Most abundant component of the viral envelope.
蛋白家族：

Epstein-Barr GP350 family
數據庫鏈接：

KEGG: vg:3783713

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