BLID Antibody

說明書

中文名稱：

BLID兔多克隆抗體
貨號：

CSB-PA818276ESR2HU
規(guī)格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA818276ESR2HU at dilution of 1:100
其他：

產(chǎn)品詳情
產(chǎn)品評價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) BLID Polyclonal antibody
Uniprot No.：

Q8IZY5
基因名：

BLID
別名：

BH3-like motif containing; cell death inducer antibody; BH3-like motif-containing cell death inducer antibody; BLID antibody; BLID_HUMAN antibody; BRCC2 antibody; breast cancer cell 2 antibody; Breast cancer cell protein 2 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Recombinant Human BH3-like motif-containing cell death inducer protein (1-108AA)
免疫原種屬：

Homo sapiens (Human)
標(biāo)記方式：

Non-conjugated
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

功能：

Functions as a proapoptotic molecule through the caspase-dependent mitochondrial pathway of cell death.
基因功能參考文獻(xiàn)：
1. Results showed that the expression of BLID is frequently downregulated in non-small cell lung tumors and cell lines and inversely correlates with miR-575 expression. PMID: 25728273
2. loss of BLID may contribute to the progression of intraductal proliferation lesions to breast cancer. PMID: 24532431
3. BRCC2 functions as a novel tumor suppressor in breast cancer and may be a potential therapeutic target for breast cancer management. PMID: 23928696
4. Frequent loss of the BLID gene is observed in early-onset breast cancer. PMID: 21846966
5. Tag single nucleotide polymorphisms near the BLID and LOC399959 genes are not susceptibility loci for high myopia in the Chinese Han population. PMID: 21031016
6. BLID upregulation resulting from a novel IGH translocation is associated with childhood B-Cell precursor acute lymphoblastic leukemia. PMID: 20544842
7. BLID is a new binding partner of Bcl-X(L) and a significant prognostic factor in breast cancer PMID: 20400521
8. BRCC2 is a novel BH3-like domain-containing protein which induces apoptosis in a caspase-dependent manner PMID: 15069058
9. BLID gene is assigned to 11p24.1. PMID: 18940476
10. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) PMID: 19779542
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亞細(xì)胞定位：

Cytoplasm. Mitochondrion. Note=Lower abundance in mitochondrion than in cytoplasm.
組織特異性：

Ubiquitously expressed.
數(shù)據(jù)庫鏈接：

HGNC: 33495

OMIM: 608853

KEGG: hsa:414899

STRING: 9606.ENSP00000453153

UniGene: Hs.686109

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