BEX3 Antibody

說(shuō)明書

中文名稱：

BEX3兔多克隆抗體
貨號(hào)：

CSB-PA015781ESR1HU
規(guī)格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA015781ESR1HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA015781ESR1HU at dilution of 1:100
其他：

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) BEX3 Polyclonal antibody
Uniprot No.：

Q00994
基因名：

BEX3
別名：

Bex antibody; BEX3 antibody; BEX3_HUMAN antibody; Brain expressed X linked 3 (mouse) homolog antibody; brain expressed; X-linked 3 antibody; Brain-expressed X-linked gene 3 antibody; Brain-expressed X-linked protein 3 antibody; DXS6984E antibody; HGR74 antibody; NADE antibody; Nerve growth factor receptor (TNFRSF16) associated protein 1 antibody; Nerve growth factor receptor associated protein 1 antibody; Nerve growth factor receptor-associated protein 1 antibody; NGFR-associated protein 1 antibody; NGFRAP1 antibody; Ovarian granulosa cell 13.0 kDa protein HGR74 antibody; ovarian granulosa cell protein (13kD) antibody; Ovarian granulosa cell protein antibody; p75NTR associated cell death executor antibody; p75NTR-associated cell death executor antibody; Protein BEX3 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Recombinant Human Protein BEX3 protein (1-111AA)
免疫原種屬：

Homo sapiens (Human)
標(biāo)記方式：

Non-conjugated
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death. May play an important role in the pathogenesis of neurogenetic diseases.
基因功能參考文獻(xiàn)：
1. Results showed that BEX3 was overexpressed in nasopharyngeal carcinoma (NPC), and indicated a unique functional role of BEX3 in mediating the sensitivity of NPC cells to cisplatin. PMID: 28083995
2. Structure-function analysis of NADE: identification of regions that mediate nerve growth factor-induced apoptosis PMID: 11830582
3. suppresses cell growth in vivo, when expressed in cultured cells PMID: 12739005
4. DRG-1 may contribute to the dopamine-induced cell growth, which is negatively regulated by NADE PMID: 16777077
亞細(xì)胞定位：

Nucleus. Cytoplasm.
蛋白家族：

BEX family
組織特異性：

Found in ovarian granulosa cells, testis, prostate and seminal vesicle tissue. High levels also detected in liver.
數(shù)據(jù)庫(kù)鏈接：

HGNC: 13388

OMIM: 300361

KEGG: hsa:27018

STRING: 9606.ENSP00000299872

UniGene: Hs.448588

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