Alpha-conotoxin LvIA Antibody
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中文名稱：Alpha-conotoxin LvIA Antibody
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貨號：CSB-PA926267XA01DWC
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Conus lividus (Livid cone) Alpha-conotoxin LvIA Polyclonal antibody
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Uniprot No.：
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基因名：Alpha-conotoxin LvIA
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別名：Alpha-conotoxin LvIA (Alpha-CTx LvIA) (Fragment)
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宿主：Rabbit
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反應種屬：Conus lividus (Livid cone)
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免疫原：Recombinant Conus lividus (Livid cone) Alpha-conotoxin LvIA protein (21-36aa)
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免疫原種屬：Conus lividus (Livid cone)
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標記方式：Non-conjugated
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
靶點詳情
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功能：Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them. This toxin blocks alpha-3-beta-2/CHRNA3-CHRNB2 nAChR with high selectivity (IC(50)=8.67 nM (on rat) and 17.5 (on human)). Has also weaker activity on alpha-6/alpha-3-beta-2-beta-3 (CHRNA6/CHRNA3-CHRNB2-CHRNB3) (IC(50)=108 nM (on rat)), alpha-6/alpha-3-beta-4 (CHRNA6/CHRNA3-CHRNB4) (IC(50)=121 nM (on rat)), alpha-3-beta-4 (CHRNA3-CHRNB4) (IC(50)=148 nM (on rat)), and alpha-7/CHRNA7 nAChRs (IC(50)=3000 nM (on rat)). When tested on mouse with hot-plate tests, this toxin significantly increases the base pain threshold and shows analgesic effects.
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亞細胞定位：Secreted.
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蛋白家族：Conotoxin A superfamily
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組織特異性：Expressed by the venom duct.
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