ATP6V0A1 Antibody
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中文名稱：ATP6V0A1兔多克隆抗體
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貨號：CSB-PA846292LA01HU
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規格：￥440
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圖片：
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Western Blot
Positive WB detected in: Rat brain tissue, Mouse brain tissue
All lanes: ATP6V0A1 antibody at 3μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 97, 96 kDa
Observed band size: 97 kDa -
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA846292LA01HU at dilution of 1:100 -
Immunofluorescent analysis of A549 cells using CSB-PA846292LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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其他：
產品詳情
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產品描述：
The ATP6V0A1 antibody is designed to recognize the ATP6V0A1 proteins from human, mouse, and rat samples. When a rabbit received an injection of the recombinant human ATP6V0A1 protein (80-260aa), an immune response occurred in the rabbit producing large amounts of antibodies against the ATP6V0A1 protein. The rabbit's blood was collected and isolated to get the anti-serum, which underwent protein G purification to obtain the high-purity ATP6V0A1 polyclonal antibody (purity 95%+). This ATP6V0A1 antibody has accessed its specificity in ELISA, WB, IHC, and IF applications.
The ATP6V0A1 protein, a subunit of the vacuolar ATPase (V-ATPase) enzyme, is specifically involved in the translocation of protons across the membrane and is essential for the proper functioning of the V-ATPase. It is responsible for maintaining the pH balance of the acidic compartments within the cell and plays a critical role in many cellular processes, including protein degradation, membrane trafficking, and ion homeostasis. Mutations in ATP6V0A1 have been linked to several disorders, including renal tubular acidosis and osteopetrosis.
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產品名稱：Rabbit anti-Homo sapiens (Human) ATP6V0A1 Polyclonal antibody
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Uniprot No.：
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基因名：
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別名：a1 antibody; ATP6N1 antibody; ATP6N1A antibody; ATP6V0A1 antibody; ATPase H+ transporting lysosomal (vacuolar proton pump) non catalytic accessory protein 1A (110/116kD) antibody; ATPase H+ transporting lysosomal non catalytic accessory protein 1 (110/116kD) antibody; ATPase H+ transporting lysosomal V0 subunit a1 antibody; ATPase H+ transporting V0 subunit a1 antibody; ATPase, H+ transporting, lysosomal, noncatalytic accessory protein 1A antibody; Clathrin coated vesicle/synaptic vesicle proton pump 116 kDa subunit antibody; Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit antibody; DKFZp781J1951 antibody; H(+) transporting two sector ATPase 116 kDa accessory protein A1 antibody; Stv1 antibody; V ATPase 116 kDa antibody; V ATPase 116 kDa isoform a1 antibody; V type proton ATPase 116 kDa subunit a antibody; V type proton ATPase 116 kDa subunit a isoform 1 antibody; V-ATPase 116 kDa isoform a1 antibody; V-type proton ATPase 116 kDa subunit a isoform 1 antibody; Vacuolar adenosine triphosphatase subunit Ac116 antibody; Vacuolar proton pump subunit 1 antibody; Vacuolar proton pump, subunit 1 antibody; Vacuolar proton translocating ATPase 116 kDa subunit A antibody; Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1 antibody; Vacuolar type H(+) ATPase 115 kDa subunit antibody; Vph1 antibody; VPP1 antibody; VPP1_HUMAN antibody
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宿主：Rabbit
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反應種屬：Human, Mouse, Rat
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免疫原：Recombinant Human V-type proton ATPase 116 kDa subunit a isoform 1 protein (80-260AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
本頁面中的產品，ATP6V0A1 Antibody (CSB-PA846292LA01HU)，的標記方式是Non-conjugated。對于ATP6V0A1 Antibody，我們還提供其他標記。見下表：
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA, WB, IHC, IF
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:5000 IHC 1:20-1:200 IF 1:50-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Required for assembly and activity of the vacuolar ATPase. Potential role in differential targeting and regulation of the enzyme for a specific organelle.
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基因功能參考文獻：
- The function of vacuolar ATPase (V-ATPase) a subunit isoforms in invasiveness of MCF10a and MCF10CA1a human breast cancer cells. PMID: 24072707
- Inhibition of lysosome degradation on autophagosome formation and responses to GMI, an immunomodulatory protein from Ganoderma microsporum. ATP6V0A1 plays an important role in mediating autophagosome-lysosome fusion. PMID: 22708544
- a series of events whereby ATP6V0A1 3'-UTR variant T+3246C functioned: ATP6V0A1 expression probably was affected through differential micro-RNA effects, altering vacuolar pH and consequently CHGA processing and exocytotic secretion. PMID: 21558123
- The mRNA levels of POLR2F, ATP6V0A1 and PRNP were evaluated by quantitative RT-PCR in 70 colorectal carcinomas and 17 normal tissue specimens and were correlated with clinicopathological parameters. PMID: 18505059
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亞細胞定位：Cytoplasmic vesicle membrane; Multi-pass membrane protein. Melanosome. Note=Coated vesicle. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
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蛋白家族：V-ATPase 116 kDa subunit family
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數據庫鏈接：
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