ATP5F1 Antibody

說明書

產(chǎn)品詳情

Uniprot No.：

P24539
基因名：

ATP5F1
別名：

AT5F1_HUMAN antibody; ATP synthase B chain mitochondrial antibody; ATP synthase subunit b antibody; ATP synthase subunit b mitochondrial antibody; ATP synthase; H+ transporting; mitochondrial F0 complex; subunit b; antibody; ATP synthase; H+ transporting; mitochondrial F0 complex; subunit b; isoform 1 antibody; ATP synthase; H+ transporting; mitochondrial F0 complex; subunit B1 antibody; ATP5F1 antibody; ATPase subunit b antibody; Cell proliferation inducing protein 47 antibody; H+ ATP synthase subunit b antibody; MGC24431 antibody; mitochondrial antibody; PIG47 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human,Mouse,Rat
免疫原：

Synthesized peptide derived from the Internal region of Human ATP5F1.
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

WB, ELISA

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:2000
ELISA	1:10000

Protocols：

Western Blotting (WB) Protocol
ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
基因功能參考文獻：
1. Down-regulation of mitochondrial ATPase by hypermethylation mechanism in chronic myeloid leukemia is associated with multidrug resistance. PMID: 20038517
2. Nitration of tyrosine residues 368 and 345 in the beta-subunit elicits FoF1-ATPase activity loss. PMID: 19650768
亞細胞定位：

Mitochondrion. Mitochondrion inner membrane.
蛋白家族：

Eukaryotic ATPase B chain family
數(shù)據(jù)庫鏈接：

HGNC: 840

OMIM: 603270

KEGG: hsa:515

STRING: 9606.ENSP00000358737

UniGene: Hs.514870

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