ARPP19 Antibody
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中文名稱：ARPP19兔多克隆抗體
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貨號：CSB-PA348885LA01HU
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規(guī)格：￥440
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圖片：
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Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA348885LA01HU at dilution of 1:100 -
Immunofluorescent analysis of HepG2 cells using CSB-PA348885LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) ARPP19 Polyclonal antibody
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Uniprot No.：
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基因名：ARPP19
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別名：ARP19 antibody; ARP19_HUMAN antibody; ARPP-19 antibody; Arpp19 antibody; cAMP-regulated phosphoprotein 19 antibody
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宿主：Rabbit
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反應(yīng)種屬：Human
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免疫原：Recombinant Human cAMP-regulated phosphoprotein 19 protein (2-105AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
本頁面中的產(chǎn)品，ARPP19 Antibody (CSB-PA348885LA01HU)，的標記方式是Non-conjugated。對于ARPP19 Antibody，我們還提供其他標記。見下表：
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA, IHC, IF
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推薦稀釋比：
Application Recommended Dilution IHC 1:20-1:200 IF 1:50-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點詳情
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功能：Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-62 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase. May indirectly enhance GAP-43 expression.
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基因功能參考文獻：
- Together, the results suggest a complex antagonistic interplay between the control of ARPP-16 by MAST3 and PKA that creates a mechanism whereby cAMP mediates PP2A disinhibition. PMID: 28613156
- Study showed that ARPP-19 promoted both proliferation and metastasis of human glioma cells and the expression of ARPP-19 and CD147 in high-grade glioma was significantly higher than that in the low-grade glioma. PMID: 27380244
- Data show that micrRNA miR-320a directly targets cAMP-regulated phosphoprotein 19 (ARPP-19) and estrogen-related receptor gamma protein (ERRgamma) in breast cancer cell lines. PMID: 25736597
- ARPP-19 may play a role in HCC pathogenesis through regulating cell proliferation. PMID: 25547487
- ARPP19 gene expression is decreased in follicular variant of papillary thyroid carcinoma. PMID: 21509594
- Decreased levels of ARPP-19 and PKA in brains of Down syndrome and Alzheimer's disease. PMID: 11771749
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亞細胞定位：Cytoplasm.
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蛋白家族：Endosulfine family
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數(shù)據(jù)庫鏈接：
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