ARFRP1 Antibody
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中文名稱(chēng)：ARFRP1兔多克隆抗體
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貨號(hào)：CSB-PA002004GA01HU
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規(guī)格：￥3,900
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：ARFRP1
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別名：ADP ribosylation factor related protein 1 antibody; ADP-ribosylation factor-related protein 1 antibody; ARF related protein 1 antibody; ARF related protein antibody; ARF-related protein 1 antibody; ARFRP_HUMAN antibody; ARFRP1 antibody; ARL 18 antibody; ARL18 antibody; ARP 1 antibody; ARP antibody; ARP1 antibody; Helicase like protein NHL antibody; MGC6837 antibody; SCG10 like protein antibody
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宿主：Rabbit
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反應(yīng)種屬：Human,Mouse,Rat
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免疫原：Human ARFRP1
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA,WB
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Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Trans-Golgi-associated GTPase that regulates protein sorting. Controls the targeting of ARL1 and its effector to the trans-Golgi. Required for the lipidation of chylomicrons in the intestine and required for VLDL lipidation in the liver.
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基因功能參考文獻(xiàn)：
- Results provide evidence that ARFRP1 is required for HCV propagation through its interaction with NS5A protein. Also, ARFRP1 is involved in the regulation of lipid droplet (LD) growth in HCV-infected cells and, recruits SNAP23 to sites in close proximity to LDs. PMID: 27550144
- ARFRP1 shifted from a predominantly cis-Golgi and endosome-to-trans-Golgi network localization to localizing both Golgi and non-Golgi vesicular structures in hNaa30-depleted cells. PMID: 28356483
- One or more of 7 genes residing in a chromosome 20q13.3 CNV region appears to influence BMI. The strongest candidate is ARFRP1. PMID: 26881067
- Propose that Arfrp1 exposes a binding site on AP-1 that recognizes the Vangl2 sorting motif for capture into a transport vesicle destined for the proximal surface of a polarized epithelial cell. PMID: 23326640
- The GTPase ARFRP1 controls the lipidation of chylomicrons in the Golgi of the intestinal epithelium. PMID: 22505585
- Data show that ADP-ribosylation factor-related protein 1 (ARFRP1) is associated mainly with the trans-Golgi compartment and the trans-Golgi network (TGN) and is an essential regulatory factor for targeting of golgin-97 and golgin-245 onto Golgi membranes. PMID: 16129887
- These data suggest that lethality of Arfrp1 knockout embryos is due to a specific disruption of protein targeting, e.g., of ARL1 and Golgin-245, to the Golgi. PMID: 17127620
- Results show that ARL1 and ARFRP1 regulate retrograde transport of Shiga toxin to the TGN and anterograde transport of VSVG from the TGN, respectively. PMID: 19224922
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亞細(xì)胞定位：Golgi apparatus. Golgi apparatus, trans-Golgi network.
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蛋白家族：Small GTPase superfamily, Arf family
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組織特異性：Found in most tissues.
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數(shù)據(jù)庫(kù)鏈接：
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