ARFGAP3 Antibody
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中文名稱：ARFGAP3兔多克隆抗體
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貨號：CSB-PA885676ESR1HU
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規(guī)格：￥440
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圖片：
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Western blot
All lanes: ARFGAP3 antibody at 4μg/ml
Lane 1: HepG2 whole cell lysate
Lane 2: Jurkat whole cell lysate
Lane 3: A549 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 57, 52 kDa
Observed band size: 57 kDa -
Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA885676ESR1HU at dilution of 1:100 -
Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA885676ESR1HU at dilution of 1:100 -
Immunoprecipitating ARFGAP3 in HepG2 whole cell lysate
Lane 1: Rabbit control IgG instead of (1μg) instead of CSB-PA885676ESR1HU in HepG2 whole cell lysate. For western blotting, a HRP-conjugated anti-rabbit IgG, specific to the non-reduced form of IgG was used as the Secondary antibody (1/50000)
Lane 2: CSB-PA885676ESR1HU (4μg) + HepG2 whole cell lysate (500μg)
Lane 3: HepG2 whole cell lysate (20μg)
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) ARFGAP3 Polyclonal antibody
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Uniprot No.：
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基因名：
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別名：ADP ribosylation factor GTPase activating protein 1 antibody; ADP ribosylation factor GTPase activating protein 3 antibody; ADP-ribosylation factor GTPase-activating protein 3 antibody; ARF GAP 3 antibody; ARFG3_HUMAN antibody; ArfGAP 3 antibody; ARFGAP1 antibody; ARFGAP3 antibody; FLJ45618 antibody
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宿主：Rabbit
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反應(yīng)種屬：Human
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免疫原：Recombinant Human ADP-ribosylation factor GTPase-activating protein 3 protein (217-516AA)
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：Non-conjugated
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA, WB, IHC, IP
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推薦稀釋比：
Application Recommended Dilution WB 1:1000-1:5000 IHC 1:20-1:200 IP 1:200-1:2000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點詳情
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功能：GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes.
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基因功能參考文獻：
- We suggest a model in which ArfGAP3 regulates Golgi association of GGA clathrin adaptors. PMID: 24076238
- our results suggest that ARFGAP3 is a novel androgen-regulated gene that can promote prostate cancer cell proliferation and migration in collaboration with paxillin. PMID: 21647875
- human ARFGAP2 and ARFGAP3 are associated with COP-I-coated vesicles and function in COP I traffic PMID: 17760859
- Differential roles of ArfGAP1, ArfGAP2, and ArfGAP3 in COPI trafficking PMID: 19015319
- ArfGAP1, ArfGAP2, and ArfGAP3 have overlapping roles in regulating COPI function in Golgi-to-ER retrograde transport. PMID: 19299515
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亞細胞定位：Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Also found on peripheral punctate structures likely to be endoplasmic reticulum-Golgi intermediate compartment.
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組織特異性：Widely expressed. Highest expression in endocrine glands (pancreas, pituitary gland, salivary gland, and prostate) and testis with a much higher expression in the testis than in the ovary.
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數(shù)據(jù)庫鏈接：
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