ANAPC5 Antibody
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中文名稱：ANAPC5兔多克隆抗體
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貨號：CSB-PA892130ESR1HU
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規格：￥440
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圖片：
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Western blot
All lanes: ANAPC5 antibody at 2μg/ml
Lane 1: 293T whole cell lysate
Lane 2: NIH/3T3 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 86, 26, 73 kDa
Observed band size: 86 kDa -
Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA892130ESR1HU at dilution of 1:100
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) ANAPC5 Polyclonal antibody
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Uniprot No.：
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基因名：
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別名：2510006G12Rik antibody; AA408751 antibody; AA536819 antibody; AA986414 antibody; ANAPC 5 antibody; ANAPC5 antibody; Anaphase promoting complex subunit 5 antibody; Anaphase-promoting complex subunit 5 antibody; Apc 5 antibody; APC5 antibody; APC5_HUMAN antibody; Cyclosome subunit 5 antibody; PDL 108 antibody; PDL108 antibody; Periodontal ligament fibroblast protein antibody; RMC1 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Anaphase-promoting complex subunit 5 protein (1-250AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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產品提供形式：Liquid
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應用范圍：ELISA, WB, IHC
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推薦稀釋比：
Application Recommended Dilution WB 1:200-1:1000 IHC 1:20-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
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基因功能參考文獻：
- coexpression of APC5 and Axin genes significantly downregulated Wnt signaling in human SW480 CRC cells and inhibited cell growth. PMID: 28731177
- Results show that Apc5 binds the poly(A) binding protein (PABP), which directly binds the internal ribosome entry site (IRES) element of platelet-derived growth factor 2 mRNA. PMID: 15082755
- APC5 and APC7 suppress E1A-mediated transformation in a CBP/p300-dependent manner, indicating that these components of the APC/C may be targeted during cellular transformation PMID: 16319895
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亞細胞定位：Nucleus. Cytoplasm, cytoskeleton, spindle.
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蛋白家族：APC5 family
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數據庫鏈接：
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