ANAPC11 Antibody
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中文名稱：ANAPC11兔多克隆抗體
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貨號：CSB-PA001696GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：
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別名：ANAPC 11 antibody; ANAPC11 antibody; Anaphase promoting complex subunit 11 (yeast APC11 homolog) antibody; Anaphase promoting complex subunit 11 antibody; Anaphase promoting complex subunit 11 homolog (yeast) antibody; Anaphase promoting complex subunit 11 homolog antibody; Anaphase-promoting complex subunit 11 antibody; Apc 11 antibody; Apc 11p antibody; APC11 anaphase promoting complex subunit 11 homolog (yeast) antibody; APC11 anaphase promoting complex subunit 11 homolog antibody; APC11 antibody; APC11_HUMAN antibody; Apc11p antibody; Cyclosome subunit 11 antibody; Hepatocellular carcinoma associated RING finger protein antibody; Hepatocellular carcinoma-associated RING finger protein antibody; HSPC 214 antibody; HSPC214 antibody; MGC882 antibody; Yeast APC 11 homolog antibody; Yeast APC11 homolog antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Human ANAPC11
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA,WB
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Together with the cullin protein ANAPC2, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex.
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基因功能參考文獻：
- siRNA targeted against Apc11 could hamper entry into G2/M phase. PMID: 23007976
- Inhibition of APC11 function by H(2)O(2) contributes to the delay in cell cycle progression through mitosis that is characteristic of cells subjected to oxidative stress PMID: 15256223
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亞細胞定位：Cytoplasm. Nucleus.
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蛋白家族：RING-box family
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組織特異性：Expressed at high levels in skeletal muscle and heart; in moderate levels in brain, kidney, and liver; and at low levels in colon, thymus, spleen, small intestine, placenta, lung and peripheral blood leukocyte.
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數據庫鏈接：
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