ANAPC10 Antibody

說明書

中文名稱：

ANAPC10兔多克隆抗體
貨號：

CSB-PA892350ESR2HU
規(guī)格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA892350ESR2HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA892350ESR2HU at dilution of 1:100
其他：

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) ANAPC10 Polyclonal antibody
Uniprot No.：

Q9UM13
基因名：

ANAPC10
別名：

ANAPC 10 antibody; anapc10 antibody; Anaphase promoting complex 10 antibody; Anaphase promoting complex subunit 10 antibody; Anaphase-promoting complex subunit 10 antibody; Apc 10 antibody; APC10 antibody; APC10_HUMAN antibody; Cyclosome subunit 10 antibody; DKFZP564L0562 antibody; Doc 1 antibody; Doc1 antibody; Doc1; S. cerevisiae; homolog of antibody; OTTHUMP00000220297 antibody; OTTHUMP00000220298 antibody; OTTHUMP00000220299 antibody; OTTHUMP00000220300 antibody; OTTHUMP00000220303 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Recombinant Human Anaphase-promoting complex subunit 10 protein (1-185AA)
免疫原種屬：

Homo sapiens (Human)
標(biāo)記方式：

Non-conjugated
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
基因功能參考文獻(xiàn)：
1. Cdc20 requires APC3 and APC8 to bind and activate the APC/C when the spindle assembly checkpoint is satisfied, but only APC8 when active, and APC10 is crucial for the destruction of cyclin B1 and securin, but not cyclin A PMID: 21336306
2. Substrates are recruited to the Anaphase-promoting complex by binding to a bipartite substrate receptor composed of Cdh1 and Doc1. PMID: 21186364
蛋白家族：

APC10 family
數(shù)據(jù)庫鏈接：

HGNC: 24077

OMIM: 613745

KEGG: hsa:10393

STRING: 9606.ENSP00000310071

UniGene: Hs.480876

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