AMPD3 Antibody

說明書

產品詳情

Uniprot No.：

Q01432
基因名：

AMPD3
別名：

Adenosine monophosphate deaminase (isoform E) antibody; Adenosine monophosphate deaminase 3 antibody; AMP aminohydrolase antibody; AMP deaminase 3 antibody; AMP deaminase isoform E antibody; Ampd3 antibody; AMPD3_HUMAN antibody; Erythrocyte AMP deaminase antibody; Erythrocyte specific AMP deaminase antibody; Erythrocyte specific protein antibody; Erythrocyte type AMP deaminase antibody; Erythroid Marker antibody; Myoadenylate deaminase antibody; OTTHUMP00000230743 antibody; OTTHUMP00000230746 antibody; OTTHUMP00000230747 antibody; OTTHUMP00000230748 antibody; OTTHUMP00000230749 antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Synthesized peptide derived from the Internal region of Human AMPD3.
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
產品提供形式：

Liquid
應用范圍：

IHC, ELISA

推薦稀釋比：

Application	Recommended Dilution
IHC	1:100-1:300
ELISA	1:40000

Protocols：

Immunohistochemistry (IHC) Protocol
ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

AMP deaminase plays a critical role in energy metabolism.
基因功能參考文獻：
1. N-terminal sequence and distal histidine residues are responsible for pH-regulated cytoplasmic membrane binding PMID: 12213808
2. mtDNA deletion coordinately induces AMP deaminase to contribute to the loss of atrial adenine nucleotides through degrading AMP excessively. PMID: 12604357
3. The primary underlying mechanism for increased catabolic flow through the AMP deaminase reaction in circulating erythrocytes of individuals with familial phosphofructokinase deficiency is Ca2+-calmodulin activation of AMP deaminase isoform E. PMID: 16670071
相關疾病：

Adenosine monophosphate deaminase deficiency erythrocyte type (AMPDDE)
蛋白家族：

Metallo-dependent hydrolases superfamily, Adenosine and AMP deaminases family
數據庫鏈接：

HGNC: 470

OMIM: 102772

KEGG: hsa:272

STRING: 9606.ENSP00000379802

UniGene: Hs.501890

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