ALX3 Antibody
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中文名稱：ALX3兔多克隆抗體
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貨號：CSB-PA001646LA01HU
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規格：￥440
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圖片：
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Immunofluorescence staining of HepG2 cells with CSB-PA001646LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) ALX3 Polyclonal antibody
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Uniprot No.：
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基因名：ALX3
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別名：ALX3Homeobox protein aristaless-like 3 antibody; Proline-rich transcription factor ALX3 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Homeobox protein aristaless-like 3 protein (11-127AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
本頁面中的產品，ALX3 Antibody (CSB-PA001646LA01HU)，的標記方式是Non-conjugated。對于ALX3 Antibody，我們還提供其他標記。見下表：
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA, IF
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推薦稀釋比：
Application Recommended Dilution IF 1:50-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Transcriptional regulator with a possible role in patterning of mesoderm during development.
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基因功能參考文獻：
- Genome scan using 250k Nsp1 array followed by exome and Sanger sequence analysis revealed a novel homozygous nonsense variant (c.604C>T, p.Gln202*) in the ALX3 gene resulting in frontorhiny in the family. This is the first mutation in the ALX3 gene, underlying frontorhiny, in Pakistani population. PMID: 29215096
- Exclusion of mutations in ALX3 gene in patients with the syndrome of frontonasal dysgenesis, callosal agenesis, basal encephalocele, and eye anomalies PMID: 22496059
- We report a novel Y214X mutation in ALX3 in frontorhiny. PMID: 22106187
- The lack of a chromosome 1-derived fragment of ALX3 in restriction landmark genomic scanning and virtual genome scans of neuroblastomas is attributable to hypermethylation. PMID: 11807986
- Alx3 participates in the regulation of insulin gene expression in pancreatic beta-cells. PMID: 16825292
- ALX3 is essential for normal facial development in humans and that deficiency causes a clinically recognizable phenotype, which we term frontorhiny. PMID: 19409524
- Rat Alx3 undergoes restrictive or permissive interactions with nuclear proteins that determine its binding to and transactivation from TAAT target sites selected in a cell-specific manner. PMID: 15226305
- Chromatin immunoprecipitation assays indicated that Alx3 in mouse pancreatic islets occupies the promoter of the mouse insulin genes. PMID: 16825292
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相關疾病：Frontonasal dysplasia 1 (FND1)
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亞細胞定位：Nucleus.
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蛋白家族：Paired homeobox family
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數據庫鏈接：
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