ALDH3B1 Antibody
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中文名稱：ALDH3B1兔多克隆抗體
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貨號：CSB-PA000861
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規(guī)格：￥1090
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圖片：
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Western Blot analysis of HuvEc cells using ALDH3B1 Polyclonal Antibody
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：ALDH3B1
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別名：ALDH3B1 antibody; ALDH7Aldehyde dehydrogenase family 3 member B1 antibody; EC 1.2.1.28 antibody; EC 1.2.1.5 antibody; EC 1.2.1.7 antibody; Aldehyde dehydrogenase 7 antibody
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宿主：Rabbit
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反應(yīng)種屬：Human
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免疫原：Synthesized peptide derived from the Internal region of Human ALDH3B1.
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：WB, IHC, ELISA
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:40000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點詳情
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功能：Oxidizes medium and long chain saturated and unsaturated aldehydes. Metabolizes also benzaldehyde. Low activity towards acetaldehyde and 3,4-dihydroxyphenylacetaldehyde. May not metabolize short chain aldehydes. Can use both NADP(+) and NAD(+) as electron acceptor. May have a protective role against the cytotoxicity induced by lipid peroxidation.
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基因功能參考文獻(xiàn)：
- the likely physiological function of ALDH3B1 is to oxidize lipid-derived aldehydes generated in the plasma membrane and not to be involved in the sphingolipid metabolism in the endoplasmic reticulum. PMID: 23721920
- protects cells from the damaging effects of oxidative stress PMID: 20699116
- The specificity of ALDH3B1 distribution may prove to be directly related to the functional role of this enzyme in human tissues. PMID: 20729348
- This study shows for the first time the functionality, expression and protective role of ALDH3B1 and indicates a potential physiological role of ALDH3B1 against oxidative stress. PMID: 17382292
- These findings provided convincing evidence that epistasis between the catechol-O-methyltransferase and aldehyde dehydrogenase 3B1 genes plays an important role in the pathogenesis of schizophrenia PMID: 19159868
- Initial characterization of human ALDH3B1 suggests a potential physiological role of this protein in oxidative stress processes. PMID: 17382292
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亞細(xì)胞定位：Cell membrane; Lipid-anchor. Note=Primarily in the plasma membrane as well as in some punctate structures in the cytoplasm.
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蛋白家族：Aldehyde dehydrogenase family
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組織特異性：Highest expression in kidney and lung.
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數(shù)據(jù)庫鏈接：
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