ACY1 Antibody
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中文名稱：ACY1兔多克隆抗體
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貨號(hào)：CSB-PA860799ESR1HU
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規(guī)格：￥440
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圖片：
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Western blot
All lanes: ACY1 antibody at 4µg/ml
Lane 1: K562 whole cell lysate
Lane 2: HepG2 whole cell lysate
Lane 3: Mouse kidney tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 46, 38, 39, 43 kDa
Observed band size: 46 kDa -
Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA860799ESR1HU at dilution of 1:100 -
Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA860799ESR1HU at dilution of 1:100
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) ACY1 Polyclonal antibody
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Uniprot No.：
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基因名：ACY1
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別名：ACY 1 antibody; ACY-1 antibody; Acy1 antibody; ACY1_HUMAN antibody; ACY1D antibody; ACYLASE antibody; Acylase I antibody; Aminoacylase 1 antibody; Aminoacylase-1 antibody; EC 3.5.1.14 antibody; epididymis secretory protein Li 5 antibody; HEL-S-5 antibody; N acyl L amino acid amidohydrolase antibody; N-acyl-L-amino-acid amidohydrolase antibody; OTTHUMP00000212459 antibody; OTTHUMP00000212462 antibody; OTTHUMP00000212463 antibody; OTTHUMP00000212464 antibody; OTTHUMP00000212465 antibody
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宿主：Rabbit
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反應(yīng)種屬：Human, Mouse
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免疫原：Recombinant Human Aminoacylase-1 protein (1-408AA)
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：Non-conjugated
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA, WB, IHC
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:2000 IHC 1:20-1:200 -
Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Catalyzes the hydrolysis of N-acetylated amino acids to acetate and free amino acids.
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基因功能參考文獻(xiàn)：
- with the elevated level in the disease progression of Chronic hepatitis B (CHB), ACY1 autoantibody may be a valuable serum biomarker for discriminating HBVrelated liver cirrhosis from CHB. PMID: 27633755
- Biochemical analysis showed absence of ACY1 enzyme activity in the patient's fibroblasts. PMID: 24117009
- ACY1 acts as a tumor suppressor in hepatocellular carcinoma. PMID: 24846301
- Report serum aminoacylase-1 as a novel biomarker with potential prognostic utility for long-term outcome in renal transplant recipients with delayed graft function. PMID: 23739232
- Case Report: ACY1-deficient patient presenting with autistic features. PMID: 20480396
- We concluded that ACY1 expression in colorectal cancer varies with stage and appears to play a role in cell proliferation and apoptosis PMID: 23317546
- These data suggest that aminoacylase expression is dysregulated in neuroblastoma. PMID: 21128244
- aminoacylase 1 proteins with the mutations p.Arg378Trp, p.Arg378Gln and p.Arg393His were also detected in Western blot analysis PMID: 21414403
- by complementing different active site mutants of human aminoacylase-1, study shows that catalysis occurs at the dimer interface PMID: 12933810
- first report of a patient with aminoacylase I deficiency PMID: 16274666
- Genetic deficiency of ACY1 leads to functional ACY1 deficiency and excretion of N-acetylated amino acids. PMID: 16465618
- Because hK1 amidase activity is significantly lower in urine of systolic HF patients, it can be supposed that activity of renal kallikrein-kinin system may be suppressed in this systolic heart failure. PMID: 17045186
- T347S variant of human Acy1 exhibited markedly increased catalytic efficiency against N-benzoylamino acids PMID: 18341290
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相關(guān)疾病：Aminoacylase-1 deficiency (ACY1D)
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亞細(xì)胞定位：Cytoplasm.
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蛋白家族：Peptidase M20A family
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組織特異性：Expression is highest in kidney, strong in brain and weaker in placenta and spleen.
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數(shù)據(jù)庫(kù)鏈接：
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