ACSM3 Antibody

說明書

中文名稱：

ACSM3兔多克隆抗體
貨號：

CSB-PA709601ESR2HU
規格：

￥440
圖片：
Western blot
All lanes: Acyl-coenzyme A synthetase ACSM3, mitochondrial antibody at 10μg/ml
Lane 1: 293T whole cell lysate
Lane 2: Mouse kidney tissue
Lane 3: A431 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 67, 50 kDa
Observed band size: 67 kDa

Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA709601ESR2HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA709601ESR2HU at dilution of 1:100
其他：

產品詳情
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靶點詳情

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) ACSM3 Polyclonal antibody
Uniprot No.：

Q53FZ2
基因名：

ACSM3
別名：

ACSM3 antibody; ACSM3_HUMAN antibody; Acyl CoA synthetase medium chain family member 3 antibody; Acyl-CoA synthetase medium-chain family member 3 antibody; Acyl-coenzyme A synthetase ACSM3 antibody; Acyl-coenzyme A synthetase ACSM3; mitochondrial antibody; Butyrate CoA ligase 3 antibody; Butyrate--CoA ligase 3 antibody; Butyryl coenzyme A synthetase 3 antibody; Butyryl-coenzyme A synthetase 3 antibody; Middle chain acyl CoA synthetase 3 antibody; Middle-chain acyl-CoA synthetase 3 antibody; mitochondrial antibody; Protein SA homolog antibody; SA (rat hypertension associated) homolog antibody; SA antibody; SA hypertension associated homolog antibody; SA; rat; homolog of antibody; SAH antibody
宿主：

Rabbit
反應種屬：

Human, Mouse
免疫原：

Recombinant Human Acyl-coenzyme A synthetase ACSM3, mitochondrial protein (387-586AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
產品提供形式：

Liquid
應用范圍：

ELISA, WB, IHC

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:2000
IHC	1:20-1:200

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Catalyzes the activation of fatty acids by CoA to produce an acyl-CoA, the first step in fatty acid metabolism. Capable of activating medium-chain fatty acids with a preference for isobutyrate among fatty acids with 2-6 carbon atoms.
基因功能參考文獻：
1. Our data provide evidence for a differential expression and regulation of the ACSM3 gene in hepatocellular carcinoma PMID: 28390038
2. Reduced ACSM3 is associated with impaired butyrate oxidation in ulcerative colitis. PMID: 21987487
3. SA gene polymorphism may be associated with the renal prognosis of immunoglobulin A nephropathy through its effect on blood pressure. Sensitivity to this gene polymorphism increases in patients with renal injury. PMID: 12484505
4. variation in SAH has a role in predisposition to overweight in hypertensives. PMID: 14567496
5. confirms recent evidence that the SAH locus is associated with obesity-related hypertension PMID: 17278971
6. family-based analyses of SA hypertension-associated homolog (SAH) gene variants did not reveal population stratification supporting an association of hypertension and gene variants PMID: 18192838
7. We conclude that, in spite of its renal expression,1-3 the human SAH gene is unlikely to have an important role in renal sodium handling. PMID: 18519841
8. SA hypertension-associated homolog(SAH) gene polymorphisms are associated with non-high-density lipoprotein cholesterol in postmenopausal women PMID: 19108963
9. left ventricular mass index and mean wall thickness , two phenotypes that are jointly influenced by blood pressure and obesity, might be related to variation in the human SAH gene PMID: 19262474
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亞細胞定位：

Mitochondrion. Mitochondrion matrix.
蛋白家族：

ATP-dependent AMP-binding enzyme family
數據庫鏈接：

HGNC: 10522

OMIM: 145505

KEGG: hsa:6296

STRING: 9606.ENSP00000289416

UniGene: Hs.706754

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