ACBD5 Antibody

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) ACBD5 Polyclonal antibody
Uniprot No.：

Q5T8D3
基因名：

ACBD5
別名：

Acbd5 antibody; ACBD5_HUMAN antibody; Acyl CoA binding domain containing 5 antibody; Acyl CoA binding domain containing protein 5 antibody; Acyl Coenzyme A binding domain containing 5 antibody; Acyl-CoA-binding domain-containing protein 5 antibody; DKFZp434A2417 antibody; Endozepine related protein antibody; KIAA1996 antibody; Membrane associated diazepam binding inhibitor antibody; OTTHUMP00000019362 antibody; OTTHUMP00000019363 antibody; OTTHUMP00000019364 antibody; OTTHUMP00000019365 antibody; RP11-85G18.5 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Acyl-CoA-binding domain-containing protein 5 protein (1-461AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產(chǎn)品，ACBD5 Antibody (CSB-PA725893HA01HU)，的標記方式是Non-conjugated。對于ACBD5 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產(chǎn)品名稱	應用
HRP	CSB-PA725893HB01HU	ACBD5 Antibody, HRP conjugated	ELISA
FITC	CSB-PA725893HC01HU	ACBD5 Antibody, FITC conjugated
Biotin	CSB-PA725893HD01HU	ACBD5 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產(chǎn)品提供形式：

Liquid
應用范圍：

ELISA, WB

推薦稀釋比：

Application	Recommended Dilution
WB	1:1000-1:5000

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters.
基因功能參考文獻：
1. ACBD5 captures VLC-CoAs on the cytosolic side of the peroxisomal membrane so that the transport of VLC-CoAs into peroxisomes and subsequent beta-oxidation thereof can proceed efficiently. PMID: 27899449
2. ACBD5-VAPB interaction regulates peroxisome-endoplasmic reticulum associations. Loss of PO-ER association perturbs PO membrane expansion and increases PO movement. PMID: 28108524
3. VAP-ACBD5-mediated contact between the endoplasmic reticulum and peroxisomes mediate organelle maintenance and lipid homeostasis. PMID: 28108526
4. Findings suggest that the ACBD5-RET rearrangement is causatively involved in the development of papillary thyroid cancer. PMID: 25175022
5. Yeast Atg37, which is homologous to human ACBD5, is involved in autophagy of peroxisomes. PMID: 24905344
6. A mutation in the acyl-coenzyme A binding domain-containing protein 5 gene (ACBD5 ) may have a role in autosomal dominant thrombocytopenia PMID: 20626622
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亞細胞定位：

Peroxisome membrane; Single-pass membrane protein.
蛋白家族：

ATG37 family
數(shù)據(jù)庫鏈接：

HGNC: 23338

OMIM: 616618

KEGG: hsa:91452

STRING: 9606.ENSP00000379568

UniGene: Hs.530597

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