ABI3 Antibody, HRP conjugated

說(shuō)明書(shū)

產(chǎn)品詳情

產(chǎn)品名稱(chēng)：

Rabbit anti-Homo sapiens (Human) ABI3 Polyclonal antibody
Uniprot No.：

Q9P2A4
基因名：

ABI3
別名：

ABI3 antibody; NESHABI gene family member 3 antibody; New molecule including SH3 antibody; Nesh antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Recombinant Human ABI gene family member 3 protein (1-366AA)
免疫原種屬：

Homo sapiens (Human)
標(biāo)記方式：

HRP
克隆類(lèi)型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA
Protocols：

ELISA Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

May inhibit tumor metastasis. In vitro, reduces cell motility.
基因功能參考文獻(xiàn)：
1. Low ABI3 expression is associated with thyroid carcinomas. PMID: 27036019
2. Data show that protein-altering changes are in PLCG2, ABI3, and TREM2 genes highly expressed in microglia and highlight an immune-related protein-protein interaction network in Alzheimer's disease. PMID: 28714976
3. Result links ABI3 to the pathogenesis and progression of some cancers and suggests that ABI3 or its pathway might have interest as therapeutic target. PMID: 21223585
4. Forced expression of NESH suppresses motility and metastatic dissemination of malignant cells. PMID: 11956071
亞細(xì)胞定位：

Cytoplasm. Note=Colocalizes with PAK2 at leading edge of cells.
蛋白家族：

ABI family
組織特異性：

Expressed in heart, lung, liver, pancreas, kidney, placenta and at low levels in brain and skeletal muscle.
數(shù)據(jù)庫(kù)鏈接：

HGNC: 29859

OMIM: 606363

KEGG: hsa:51225

STRING: 9606.ENSP00000225941

UniGene: Hs.130719

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