Mouse IgG Fc fragment

文獻引用 (1)

中文名稱：

小鼠IgG Fc片段
貨號：

CSB-NP005801m
說明書：

MSDS Datasheet
規格：

￥2256
圖片：
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
其他：

產品詳情
產品評價
引用文獻
問答及客戶評論

產品詳情

純度：

>95% (SDS-PAGE)
生物活性：

Not test
別名：

Fragment crystallizable region
來源：

Mouse serum IgG digested with papain
氨基酸序列

Full length protein
產品提供形式：

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Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

PBS, pH 7.4
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

3weeks
產品描述：

Mouse IgG Fc fragment is a native protein with full length. This protein is purified from mouse serum IgG digested with papain. Its purity was determined by SDS-PAGE and reached up to 95%. It is presented the mass molecule around 30 kDa visualized on the gel. It has been validated in ELISA, WB and SDS-PAGE applications.
The fragment crystallizable region (Fc region) is the tail region of an antibody that interacts with cell surface receptors known as Fc receptors and some proteins of the complement system. This property allows antibodies to activate the immune system. The Fc regions of IgG bear a highly conserved N-glycosylation site. Glycosylation of the Fc fragment is essential for Fc receptor-mediated activity. The N-glycans attached to this site are predominantly core-fucosylated diantennary structures of the complex type.
Datasheet & COA：

Please contact us to get it.

引用文獻

A versatile platform for the tumor-targeted delivery of immune checkpoint-blocking immunoglobin G Jie Fan,Journal of controlled release : official journal of the Controlled Release Society,2021

產品評價

問答及客戶評論

■ 常見問題解答

I am wondering if I can know the molecular weight and amino acid sequence of mouse IgG Fc fragment.

Thanks for your inquiry. According to the product name you provided, the product should be a native protein instead of peptide.
CSB-NP005801m Mouse IgG Fc
This is a native protein and its molecular weight is 30-32KDa. There is no amino acid sequence.

It is stated as native protein in the information sheet sorry I mixed peptide and protein. Do you mean you don't have the information on its amino acid sequence? If that's the case, do you have any suggestion on data bank that I can search since I am not a protein person?

Very nice to receive your quick response.
You could use imgt database to search the sequence of CSB-NP005801m.
We have tried to search the sequence of this protein in imgt database but haven't found. You could have a try.
We're not sure why you would like to know the sequence of this native protein, because almost no customer ask for this information.
Native protein is naturally extracted and the sequence will not change, and will not make any influence on experiment.

CSB-NP005801m和CSB-NP005201Rb是否都是和木瓜蛋白酶消化？貴公司是否有人種屬IgG？

CSB-NP005801m和CSB-NP005201Rb 這兩種天然蛋白由木瓜蛋白酶催化分解獲得人種屬IgG Fc fragment：CSB-NP005401h Human IgG Fc fragment

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