Mono-Methyl-Histone H3(K79) Monoclonal Antibody
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中文名稱(chēng)：單甲基-組蛋白H3(K79)鼠單克隆抗體
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貨號(hào)：CSB-MA000251
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規(guī)格：￥1090
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圖片：
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Western blot analysis of 1) Hela, 2) Rat Testis tissue, 3) Raw264.7, diluted at 1:2000.
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其他：
產(chǎn)品詳情
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產(chǎn)品描述：Mono-Methyl-Histone H3(K79) Monoclonal Antibody（CUSABIO貨號(hào)：CSB-MA000251）是一款針對(duì)組蛋白H3第79位賴(lài)氨酸單甲基化修飾（H3K79me1）的高特異性科研試劑，適用于探索表觀遺傳調(diào)控機(jī)制及染色質(zhì)動(dòng)態(tài)研究。H3K79甲基化作為重要的表觀遺傳標(biāo)記，廣泛參與基因轉(zhuǎn)錄調(diào)控、DNA損傷修復(fù)及細(xì)胞周期進(jìn)程，其異常表達(dá)與腫瘤發(fā)生、干細(xì)胞分化等生物學(xué)過(guò)程密切相關(guān)。本產(chǎn)品采用雜交瘤技術(shù)制備，經(jīng)ELISA和Western Blot多平臺(tái)驗(yàn)證，可精準(zhǔn)識(shí)別人類(lèi)、小鼠及大鼠樣本中H3K79me1修飾位點(diǎn)，具有優(yōu)異的批間一致性和低交叉反應(yīng)特性，滿足表觀基因組學(xué)、癌癥機(jī)理研究等領(lǐng)域?qū)Ω呔瓤贵w的需求。研究者可將其應(yīng)用于染色質(zhì)免疫共沉淀（ChIP）、蛋白質(zhì)互作分析等實(shí)驗(yàn)，深入解析表觀遺傳修飾在疾病模型或發(fā)育生物學(xué)中的功能調(diào)控網(wǎng)絡(luò)，為靶向藥物開(kāi)發(fā)提供基礎(chǔ)研究工具。該抗體作為表觀遺傳學(xué)研究的核心試劑，適用于基因組穩(wěn)定性研究、細(xì)胞命運(yùn)決定機(jī)制探索等前沿課題，是生命科學(xué)領(lǐng)域探索H3K79甲基化功能的理想選擇。
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Uniprot No.：
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宿主：Mouse
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反應(yīng)種屬：Human,Mouse,Rat
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免疫原：Synthetic Peptide
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免疫原種屬：H, M, R
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標(biāo)記方式：Non-conjugated
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抗體亞型：IgG
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克隆號(hào)：3E10
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA,WB
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:5000 -
Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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