MYCBP Monoclonal Antibody
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中文名稱：MYCBP鼠單克隆抗體
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貨號：CSB-MA8587101A0m
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規格：￥1320
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圖片：
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Immunohistochemical of paraffin-embedded Human testis tissue using CSB-MA8587101A0m at dilution of 1:200.
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其他：
產品詳情
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產品描述：MYCBP單克隆抗體（CUSABIO貨號：CSB-MA8587101A0m）是針對MYC結合蛋白（MYCBP）研發的高特異性科研試劑，該靶點作為MYC原癌基因的關鍵互作蛋白，在細胞周期調控、DNA損傷修復及腫瘤發生機制中具有重要研究價值。本產品采用雜交瘤技術制備，經ELISA與免疫組化（IHC）雙平臺驗證，可精準識別人類來源的MYCBP抗原表位，適用于腫瘤生物學、分子病理學等領域的蛋白質相互作用研究。科研人員可將其應用于腫瘤組織切片中MYCBP蛋白的定位分析、體外培養細胞模型的蛋白表達水平檢測，以及基于ELISA平臺的定量分析實驗。產品經過嚴格的質控流程，為探索MYC信號通路在腫瘤微環境調控、耐藥機制等前沿課題提供可靠工具。該抗體已成功應用于乳腺癌、結直腸癌等實體瘤研究的文獻報道中，是癌癥標志物篩選和分子機理研究的優選試劑。
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產品名稱：mouse anti-Homo sapiens (Human) MYCBP monoclonal antibody
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Uniprot No.：
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基因名：MYCBP
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別名：AMY 1 antibody; AMY-1 antibody; AMY1 antibody; Associate of Myc 1 antibody; C myc binding protein antibody; C-Myc-binding protein antibody; Cmyc binding protein antibody; MYCBP antibody; MYCBP_HUMAN antibody
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宿主：mouse
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反應種屬：Human
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免疫原：Recombinant Human MYCBP Protein
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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克隆類型：monoclonal
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純化方式：>95%,protein G purifed
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克隆號：1D5D5
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
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產品提供形式：liquid
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應用范圍：ELISA,IHC
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推薦稀釋比：
Application Recommended Dilution IHC 1:50-1:500 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：May control the transcriptional activity of MYC. Stimulates the activation of E box-dependent transcription by MYC.
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基因功能參考文獻：
- c-Myc expression is reduced in pterygium compared with normal conjunctiva. PMID: 22050566
- Suppression of telomerase activity mediated by PinX1 is involved in the Mad1/c-Myc pathway. PMID: 20544396
- miR-22 acts as a tumor suppressor through direct repression of MYCBP expression and subsequent reduction of oncogenic c-Myc activities. PMID: 20562918
- identified a novel AMY-1-binding protein, AAT-1, and determied its expression profiles, genes, and cellular localization; results showed that AAT-1 was specifically expressed in the testis throughout spermatogenesis and was also present in mature sperm PMID: 12223483
- interacts with S-AKAP84 and AKAP95 in the cytoplasm and the nucleus, respectively, and inhibits enzyme acdtivity by preventing binding of its catalytic subunit to A-kinase-anchoring protein (AKAP) complex PMID: 12414807
- AMY-1 coordinates ADP-Ribosylation Factors-mediated membrane trafficking and signaling pathways. PMID: 16866877
- An important role for MBP-1 in the altered cell proliferation and energy utilization that occur in response to an altered glucose concentration. PMID: 17595061
- AMY-1 was localized in the mitochondria of HeLa and sperm in association with AKAP149 and S-AKAP84, respectively. These results suggest that AMY-1 plays a role in spermatogenesis PMID: 11483602
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亞細胞定位：Cytoplasm. Nucleus. Mitochondrion. Note=Translocates into the nucleus in the S phase of the cell cycle upon an increase of MYC expression. Found in the mitochondria when associated with AKAP1.
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蛋白家族：AMY1 family
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組織特異性：Highly expressed in heart, placenta, pancreas, skeletal muscle and kidney. Also present at low levels in lung.
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數據庫鏈接：
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