G4S linker Monoclonal Antibody
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中文名稱：G4S linker CAR檢測工具
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貨號：CSB-MA186062I1m
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規(guī)格：￥3000
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圖片：
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The Binding Activity of G4S linker with Anti-G4S linker antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Three recombinant proteins containing G4S linker at 2 μg/mL can bind Anti-G4S linker antibody. The EC50 is 5.223 to 18.40 ng/mL, 17.89 to 45.51 ng/mL and 2.705 to 8.752 ng/mL. -
Untransfected HEK-293F cells (green line) and transfected scFv-based Anti-CD19 CAR containing a G4S linker stable cells (red line) were stained with anti-G4S linker antibody (2μg/1*106cells), washed and then followed by APC-conjugated anti-Mouse IgG Fc antibody and analyzed with flow cytometry.
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其他：
產(chǎn)品詳情
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產(chǎn)品描述：CUSABIO貨號：CSB-MA186062I1m人源G4S linker單克隆抗體是CAR-T細胞治療研究領(lǐng)域的高特異性檢測工具，專為識別嵌合抗原受體結(jié)構(gòu)中的G4S柔性連接子設(shè)計。該抗體采用雜交瘤技術(shù)制備，可特異性結(jié)合CAR分子中連接抗體重鏈（VH）與輕鏈（VL）的關(guān)鍵結(jié)構(gòu)域，適用于ELISA和流式細胞術(shù)（FC 1:50-1:200）兩種檢測平臺。作為通用型CAR陽性率檢測試劑，其核心價值在于支持CAR-X細胞療法（包括CAR-T、CAR-NK、CAR-M等）的研發(fā)質(zhì)控環(huán)節(jié)，幫助科研人員精準評估工程化免疫細胞的CAR表達水平，為細胞制備工藝優(yōu)化、功能驗證及體內(nèi)外藥效研究提供可靠數(shù)據(jù)支撐。該產(chǎn)品嚴格滿足科研級抗體標準，尤其適用于腫瘤免疫治療基礎(chǔ)研究、新型CAR結(jié)構(gòu)開發(fā)及細胞治療產(chǎn)品的臨床前研究體系驗證。
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基因名：G4S linker
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別名：G4S, G4S linker
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宿主：Mouse
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反應(yīng)種屬：Homo sapiens (Human)
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免疫原：G4S-BSA
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標記方式：Non-conjugated
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克隆類型：Monoclonal
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抗體亞型：IgG2b
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純化方式：>95%, Protein G purified
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克隆號：11A12E7
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA, FC
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推薦稀釋比：
Application Recommended Dilution FC 1:50-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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