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中文名稱：綿羊黃體生成素（LH）酶聯免疫試劑盒
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貨號：CSB-E14019Sh
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規格：96T/48T
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價格：￥4200/￥3000
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其他：
產品詳情
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產品描述：綿羊黃體生成素（LH）酶聯免疫試劑盒（CSB-E14019Sh）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿、組織勻漿樣本中的LH含量。LH即促黃體生成素，是腺垂體分泌的促性腺激素。其在生殖生理中背景重要，參與調節卵巢和睪丸功能。研究機制方面，它作用于性腺細胞表面受體，促進性激素合成與分泌，在女性排卵及黃體形成等過程、男性睪酮生成中發揮關鍵作用。該產品適用于綿羊繁殖周期監測、卵巢功能評估、生殖疾病模型研究等科研場景，為畜牧繁殖管理、激素調控機制探索及生殖健康相關基礎研究提供可靠工具。本品僅用于科研，不用于臨床診斷，產品具體參數及操作步驟詳見產品說明書。
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別名：LHBLutropin subunit beta ELISA Kit; Lutropin beta chain ELISA Kit; Interstitial cell-stimulating hormone ELISA Kit; Luteinizing hormone subunit beta ELISA Kit; LH-B ELISA Kit; LSH-B ELISA Kit; LSH-beta) [Cleaved into: LH beta-1; LH beta-2; LH beta-3] ELISA Kit
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縮寫：LH
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Uniprot No.：
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種屬：Ovis aries (Sheep)
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樣本類型：serum, plasma, tissue homogenates
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檢測范圍：
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反應時間：1-5h
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樣本體積：50-100ul
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檢測波長：450 nm
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研究領域：Signal Transduction
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測定原理：quantitative
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測定方法：Sandwich
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精密度：
Intra-assay Precision (Precision within an assay): CV%<15%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV%<15%
Three samples of known concentration were tested in twenty assays to assess.
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線性度：
To assess the linearity of the assay, samples were spiked with high concentrations of Sheep Luteinizing Hormone(LH) in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
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數據處理：
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貨期：3-5 working days
引用文獻
- Immunization against Kisspeptin-54 perturb hypothalamic-pituitary-testicular signaling pathway in ram lambs TeketayWassie, et al,Theriogenology,2018
- Dose-dependent effects of luteinizing hormone and follicle stimulating hormone on in vitro maturation, apoptosis, secretion function and expression of follicle Wei, S.et al,South African Journal of Animal Science,2018
- Annual Change of Reproductive Hormones in Female Angora Goats Erkan Pehlivan.et al,,2022
- Effect of immunization against GnRH on hypothalamic and testicular function in rams Han X.et al,Theriogenology,2015
- Evidence for a role of KISS-1/GPR54 system in decreased luteinizing hormone (LH) secretion in fasted prepubertal ewes J Wang, H zhou, T Zhang,African Journal of Biotechnology,2012
- GnRHa active immunity regulates expression of LHR protein and development of uteri in ewes Suocheng Wei et al,Journal of Applied Animal Research,2013
- Effect of Peripheral Administration of Kisspeptin-10 on Dynamic LH Secretion in Prepubertal Ewes /,Asian-Aust. J. Anim. Sci,2012
產品評價
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靶點詳情
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功能：Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. The LH alpha 3/LH beta 3 heterodimer was shown to have potent renotropic and weak gonadotropic activity.
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基因功能參考文獻：
- Data indicate that the neuropeptide RFamide-related peptide 3 (RFRP-3) has no effect onluteinizing hormone secretion. PMID: 26862995
- This study indicates that endogenous opiates play a crucial role in the mechanism inhibiting GnRH/LH axis activity in lactating sheep and that the ligands for mu opioid receptor may have the highest inhibitory effect. PMID: 23953813
- Data suggest dietary components (phytoestrogens here) down-regulate basal secretion/total production of follicle stimulating hormone (CGA+FSHB) yet up-regulate gonadotropin-releasing hormone agonist-induced LH (CGA+LHB) secretion in gonadotrophs. PMID: 24050980
- These results indicate that the reproductive system can respond acutely to infusion of metabolic fuels such as propionate, although a sustained recovery of pulsatile LH secretion requires more than an increase in this single metabolic substrate. PMID: 21668532
- In ewes, infusion with genistein decreased the level of LHbeta in the adenohypophysis. PMID: 15531133
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亞細胞定位：Secreted.
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蛋白家族：Glycoprotein hormones subunit beta family
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數據庫鏈接：
KEGG: oas:443395
UniGene: Oar.442
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