Rat dopamine,DA ELISA Kit

Rat dopamine,DA ELISA Kit

產(chǎn)品詳情

引用文獻

產(chǎn)品評價

靶點詳情

產(chǎn)品詳情

引用文獻

產(chǎn)品評價

相關(guān)產(chǎn)品

靶點詳情

Most popular with customers

產(chǎn)品中心

信號通路

技術(shù)信息

聯(lián)系信息

文獻引用 (50) 說明書下載

中文名稱：

大鼠多巴胺(DA)酶聯(lián)免疫試劑盒
貨號：

CSB-E08660r
規(guī)格：

96T/48T
價格：

￥3900/￥2500
促銷：
其他：

產(chǎn)品詳情
產(chǎn)品評價
引用文獻
相關(guān)產(chǎn)品
靶點詳情

產(chǎn)品描述：

大鼠多巴胺(DA)酶聯(lián)免疫試劑盒（CSB-E08660r）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿、組織勻漿樣本中的DA含量。DA即多巴胺，是一種重要神經(jīng)遞質(zhì)。其在調(diào)節(jié)運動、情緒、獎賞等生理功能中有關(guān)鍵作用。研究機制上，圍繞其合成、釋放、再攝取等過程，探究與帕金森病、精神分裂癥等疾病聯(lián)系，以開發(fā)針對性治療藥物。試劑盒檢測范圍為0.156 ng/mL-10 ng/mL，該產(chǎn)品適用于神經(jīng)生物學、藥理學等科研領(lǐng)域，可探究帕金森模型動物DA水平變化、精神疾病相關(guān)神經(jīng)遞質(zhì)動態(tài)，或評估藥物干預對DA代謝通路的影響。本品僅用于科研，不用于臨床診斷，產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
別名：

N/A
縮寫：

DA
種屬：

Rattus norvegicus (Rat)
樣本類型：

serum, plasma, tissue homogenates
檢測范圍：

0.156 ng/mL-10 ng/mL
靈敏度：

0.039 ng/mL
反應時間：

1-5h
樣本體積：

50-100ul
檢測波長：

450 nm
研究領(lǐng)域：

Neuroscience
測定原理：

quantitative
測定方法：

Sandwich

精密度：

線性度：

To assess the linearity of the assay, samples were spiked with high concentrations of rat DA in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
	Sample	Serum(n=4)
1:5	Average %	86
	Range %	84-96
1:10	Average %	95
	Range %	91-100
1:20	Average %	84
	Range %	81-88
1:40	Average %	92
	Range %	88-96

回收率：

The recovery of rat DA spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.

Sample Type	Average % Recovery	Range
Serum (n=5)	91	87-95
EDTA plasma (n=4)	96	94-98

標準曲線：

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

ng/ml	OD1	OD2	Average	Corrected
10	2.174	2.280	2.227	2.076
5	1.784	1.789	1.787	1.636
2.5	1.250	1.276	1.263	1.112
1.25	0.841	0.875	0.858	0.707
0.625	0.435	0.465	0.450	0.299
0.312	0.287	0.308	0.298	0.147
0.156	0.208	0.223	0.216	0.065
0	0.152	0.150	0.151

數(shù)據(jù)處理：

ELISA操作視頻及標曲繪制軟件下載
貨期：

3-5 working days

Neuroprotective Effects of Alpha-Lipoic Acid Against Behavioral Toxicity, Oxidative and Inflammatory Damage Caused by Titanium Dioxide Nanoparticles MA Khedr, SE El-Kazaz, RR Rashed,Biological Trace Element Research,2025
EFFICACY OF NIGELLA SATIVA, OLIVE LEAF EXTRACTS, CINNAMALDEHYDE, AND ITS NANO-EMULSION ON ALLEVIATION OF DEPRESSION IN MNCL2 … R AHMED, F KHALIL, HH EMEASH,Assiut Veterinary Medical Journal,2025
α-Bisabolol alleviates doxorubicin-induced cognitive dysfunction in rats via enhancing the hippocampal BDNF/TrKB signaling and inhibiting neuroinflammation ST Elazab, WH Hsu,Frontiers in Pharmacology,2025
Dabigatran Combined With Benztropine Ameliorates Cobalt Chloride-Induced Parkinsonism in Rats, Restores Protease Activated Receptor 1 (PAR1), and Mitigates Oxidative Stress S Abdelmissih, LA Rashed, MSI Negm, WM Sayed,Cureus,2025
Study of Neuroinflammation and Oxidative Stress Induced by Energy Drinks Consumption A Dose-Dependent Study S Sherif, N Gamal, O Abdelnaby, A Hamza,Azerbaijan Medical Journal,/
Neuroprotective Effects of Bryophyllum pinnatum against Ketamine-Induced Neurotoxicity in Wistar Rats: Neurochemical, Oxidative Stress, and Histological Investigation PO Uahomo, JC Isirima,International Neuropsychiatric Disease Journal,2024
Neuroprotective effect of Lannea egregia Alkaloid-rich Leaf Extracts in Streptozotocin-induced Diabetic Rats BO Ajiboye, BE Ekundayo, AW Salami, AO Osukoya,Toxicology Reports,2024
Boosting Physical Performance in SD Rats through Brain-Targeted Delivery of Caffeine-Loaded Transferrin Liposomes H Yun,Heliyon,2024
The analgesic effects of insulin and its disorders in streptozotocin‐induced short‐term diabetes AM Basatinya,Physiological reports,2024
A Complex Interplay of DJ-1, LRRK2, and Nrf2 in the Regulation of Mitochondrial Function in Cypermethrin-Induced Parkinsonism A Sarkar,Molecular neurobiology,2023
Chitosan-coated nanostructured lipid carriers for effective brain delivery of Tanshinone IIA in Parkinson’s disease: interplay between nuclear factor-kappa β and cathepsin B DM Hassan,Drug delivery and translational research,2023
Targeting α7-nAChR by galantamine mitigates reserpine-induced fibromyalgia-like symptoms in rats: involvement of cAMP/PKA, PI3K/AKT, and M1/M2 microglia?… AA Atta,European journal of pharmacology,2023
Reactive astrocytes targeting with oral vitamin A: Efficient neuronal regeneration for Parkinson's disease treatment and reversal of associated liver fibrosis NS El‐Mezayen,CNS neuroscience & therapeutics,2023
Gut microbiota-SCFAs-brain axis associated with the antidepressant activity of berberine in CUMS rats MN Huang,Journal of affective disorders,2023
p-CREB and p-DARPP-32 orchestrating the modulatory role of cAMP/PKA signaling pathway enhanced by Roflumilast in rotenone-induced Parkinson's disease in rats RM Essam,Chemico-biological interactions,2023
Cilostazol Alleviates NLRP3 Inflammasome–Induced Allodynia/Hyperalgesia in Murine Cerebral Cortex Following Transient Ischemia: Focus on TRPA1/Glutamate and Akt/Dopamine/BDNF/Nrf2 Trajectories OS Zaki,Molecular Neurobiology,2022
Alhagi maurorum Ethanolic Extract Rescues Hepato-Neurotoxicity and Neurobehavioral Alterations Induced by Lead in Rats via Abrogating Oxidative Stress and the Caspase-3-Dependent Apoptotic Pathway TM Saber,Antioxidants,2022
Anti-aging trait of whey protein against brain damage of senile rats ME El-Beeh,Anti-aging trait of whey protein against brain damage of senile rats,2022
Design and synthesis of benzo[d]thiazol-2-yl-methyl-4-(substituted)-piperazine-1-carbothioamide as novel neuronal nitric oxide inhibitors and evaluation of their neuroprotecting effect in 6-OHDA-induced unilateral lesioned rat model of Parkinson's disease S Agrawal,Biomedicine & Pharmacotherapy,2022
Neuroprotective effect of peanut against oxidative stress in streptozotocin-induced diabetic rats NH Mohamed,Egyptian Journal of Basic and Applied Sciences,2022
Cilostazol Alleviates NLRP3 Inflammasome–Induced Allodynia/Hyperalgesia in Murine Cerebral Cortex Following Transient Ischemia: Focus on TRPA1/Glutamate and Akt/Dopamine/BDNF/Nrf2 Trajectories OS Zaki,Molecular neurobiology,2022
Molecular evidence of the amelioration of toluene induced encephalopathy by human breast milk mesenchymal stem cells OIA Hamid,Scientific reports,2022
Neurotoxic Effect of Fipronil in Male Wistar Rats: Ameliorative Effect of L-Arginine and L-Carnitine YK Mahmoud,Biology,2021
Altered hippocampal function and cytokine levels in a rat model of Gulf War illness Joyce G. Rohan,Life Sciences,2021
Targeting ROS-Dependent AKT/GSK-3β/NF-κB and DJ-1/Nrf2 Pathways by Dapagliflozin Attenuates Neuronal Injury and Motor Dysfunction in Rotenone-Induced Parkinson’s Disease Rat Model Marwa M. Safar,ACS Chemical Neuroscience,2021
Influence of progestational stress on BDNF and NMDARs in the hippocampus of male offspring and amelioration by Chaihu Shugan San Xin-xing Wang,Biomedicine & Pharmacotherapy,2021
Unique Novel role of Adropin in the gastric Ulcer in a rotenone-induced Rat model of Parkinson's disease RE Abo El gheit,ACS Chemical Neuroscience,2020
Effect of Solanum macrocarpon Linn leaf aqueous extract on the brain of an alloxan-induced rat model of diabetes MA Okesola,J Int Med Res,2020
Saponin extract of Baihe-Zhimu Tang ameliorates depression in chronic mild stress rats D Jia,Journal of Functional Foods,2020
Mechanism of the neuroprotective effect of GLP-1 in a rat model of Parkinson's with pre-existing diabetes Elbassuoni E A, et al,Neurochemistry International,2019
Correlation between angiotensin 1-7-mediated Mas receptor expression with motor improvement, activated STAT3/SOCS3 cascade, and suppressed HMGB-1/RAGE/NF-κB signaling in 6-hydroxydopamine hemiparkinsonian rats Mostafa A.Rabie, et al,Biochemical Pharmacology,2019
Protective effects of betanin against paracetamol and diclofenac induced neurotoxicity and endocrine disruption in rats Motawi TK, et al,Biomarkers,2019
Comparing the effects of progressive and mild intensity treadmill running protocols on neuroprotection of parkinsonian rats Mohammadi ZF,Life Sciences,2019
Sitagliptin and Liraglutide Modulate L-dopa Effect and Attenuate Dyskinetic Movements in Rotenone-Lesioned Rats Badawi GA, et al,Neurotoxicity Research,2019
A pharmacological composition for induction of a reversible torpor-like state and hypothermia in rats Zakharova NM, et al,Life Sciences,2019
Social defeat stress before pregnancy induces depressive-like behaviours and cognitive deficits in adult male offspring: correlation with neurobiological changes Wei S.et al,BMC Neuroscience,2018
INCREASED LOCOMOTOR ACTIVITY IN ESTROGEN-\TREATED OVARIECTOMIZED RATS IS ASSOCIATED WITH NUCLEUS ACCUMBENS DOPAMINE AND IS NOT REDUCED BY DIETARY SODIUM DEPRIVATION Enith Espinosa.et al,INTEGR ZOOL,2018
Neuroprotective effect of IDPU (1-(7-imino-3-propyl-2,3-dihydrothiazolo [4,5-d]pyrimidin-6(7H)-yl)urea) in 6-OHDA induced rodent model of hemiparkinson’s disease NamrataKumari.et al,Neuroscience Letters,2018
A urinary metabolomics (GC-MS) strategy to evaluate the antidepressant-like effect of chlorogenic acid in adrenocorticotropic hormone-treated rats Le Zhao.et al, RSC Adv,2018
Effect of Yulangsan Polysaccharide on the Reinstatement of Morphine-Induced Conditioned Place Preference in Sprague?Dawley Rats Chen C.et al,Neurochem Res,2018
Angiotensin 1-7 ameliorates 6-hydroxydopamine lesions in hemiparkinsonian rats through activation of MAS receptor/PI3K/Akt/BDNF pathway and inhibition Rabie, Mostafa A.et al,Biochemical pharmacology,2018
Impact of anger emotional stress before pregnancy on adult male offspring Wei S.et al,Oncotarget,2017
Antidepressant-like effect of lipid extract of Channa striatus in postpartum model of depression in rats Abdul Shukkoor MS.et al,Evid Based Complement Alternat Med,2016
Forced Exercise in Combination with 1, 25-dihydroxyvitamin D3 Before Induction of 6-hydroxydopamine Protects Dopaminergic Neurons in Rats Model of Parkinson’s Disease Fatemeh Mirfakhrai .et al,Zahedan Journal of Research in Medical Sciences,2017
The role of apitoxin in alleviating propionic acid-induced neurobehavioral impairments in rat pups: The expression pattern of Reelin gene Daghestani MH.et al,Biomed Pharmacother.,2017
Neurotoxic effects of silver nanoparticles and the protective role of rutin Ahmed MM.et al,Biomed Pharmacothe,2017
Sitagliptin and liraglutide reversed nigrostriatal degeneration of rodent brain in rotenone-induced Parkinson’s disease Badawi GA.et al,Inflammopharmacology.,2017
A novel GLP-1/GIP dual receptor agonist protects from 6-OHDA lesion in a rat model of Parkinson's disease Jalewa J.et al,Neuropharmacology.,2017
Modulatory effects of resveratrol on endoplasmic reticulum stress-associated apoptosis and oxido-inflammatory markers in a rat model of rotenone-induced Parkinson's disease Gaballah HH.et al,Chem Biol Interact.,2016
Comparative protective effects of royal jelly and cod liver oil against neurotoxic impact of tartrazine on male rat pups brain Mohamed AA. et al,Acta Histochem,2015

收起更多

最新研究進展：

DA是多巴胺的簡稱，是一種重要的神經(jīng)遞質(zhì)。近年來，研究人員發(fā)現(xiàn)DA參與了多種生理和病理過程，如運動功能、認知能力、代謝性疾病、精神疾病等。同時，DA與多種神經(jīng)系統(tǒng)疾病的發(fā)病機制密切相關(guān)，如帕金森病、精神分裂癥等。

Intra-assay Precision (Precision within an assay): CV%<8%

Three samples of known concentration were tested twenty times on one plate to assess.

Inter-assay Precision (Precision between assays): CV%<10%

Three samples of known concentration were tested in twenty assays to assess.