Rat amyloid beta peptide 1-42,Aβ1-42 ELISA Kit

Rat amyloid beta peptide 1-42,Aβ1-42 ELISA Kit

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中文名稱：

大鼠β淀粉樣蛋白1-42(Aβ1-42)酶聯免疫試劑盒
貨號：

CSB-E10786r
規格：

96T/48T
價格：

￥3900/￥2500
其他：

CUSABIO Wins 2024 Bioz Rapid Star? Award in the ELISA category

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產品描述：

大鼠β淀粉樣蛋白1-42(Aβ1-42)酶聯免疫試劑盒（CSB-E10786r）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿、組織勻漿樣本中的Aβ1-42含量。Aβ1-42是重要的阿爾茨海默病相關靶點。其在腦內異常聚集形成淀粉樣斑塊，被認為是該病發病的關鍵病理特征。研究聚焦于其生成、清除機制、神經毒性作用等，期望通過干預Aβ1-42代謝過程開發有效治療手段。試劑盒檢測范圍為0.9 pg/mL-60 pg/mL，適用于神經科學領域的基礎研究，如阿爾茨海默病動物模型中Aβ1 - 42的動態變化觀察、藥物干預效果評價或病理機制探索，其寬泛的樣本兼容性可滿足腦組織、血液等多種生物樣本的檢測需求。本品僅用于科研，不用于臨床診斷，產品具體參數及操作步驟詳見產品說明書。
別名：

Amyloid beta 42(ABeta 42),amyloid beta peptide 1-42,Aβ1-42,amyloid βpeptide 1-42
縮寫：

Aβ1-42
種屬：

Rattus norvegicus (Rat)
樣本類型：

serum, plasma, tissue homogenates
檢測范圍：

0.9 pg/mL-60 pg/mL
靈敏度：

0.225 pg/mL
反應時間：

1-5h
樣本體積：

50-100ul
檢測波長：

450 nm
研究領域：

Neuroscience
測定原理：

quantitative
測定方法：

Sandwich

精密度：

線性度：

To assess the linearity of the assay, samples were spiked with high concentrations of rat Aβ1-42 in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
	Sample	Serum(n=4)
1:1	Average %	87
	Range %	83-90
1:2	Average %	94
	Range %	90-98
1:4	Average %	101
	Range %	97-104
1:8	Average %	96
	Range %	93-99

回收率：

The recovery of rat Aβ1-42 spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.

Sample Type	Average % Recovery	Range
Serum (n=5)	94	89-98
EDTA plasma (n=4)	100	95-105

標準曲線：

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

pg/ml	OD1	OD2	Average	Corrected
60	2.281	2.274	2.278	2.136
30	1.599	1.576	1.588	1.446
15	0.967	0.924	0.946	0.804
7.5	0.538	0.528	0.533	0.391
3.75	0.395	0.371	0.383	0.241
1.8	0.321	0.312	0.317	0.175
0.9	0.235	0.250	0.243	0.101
0	0.141	0.143	0.142

數據處理：

ELISA操作視頻及標曲繪制軟件下載
貨期：

3-5 working days

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Intra-assay Precision (Precision within an assay): CV%<8%

Three samples of known concentration were tested twenty times on one plate to assess.

Inter-assay Precision (Precision between assays): CV%<10%

Three samples of known concentration were tested in twenty assays to assess.