Rat alpha-1-microglobulin/bikunin precursor (AMBP) ELISA kit
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中文名稱(chēng)：大鼠α1微球蛋白/bikunin蛋白前體(AMBP)酶聯(lián)免疫試劑盒
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貨號(hào)：CSB-EL001654RA
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規(guī)格：96T/48T
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價(jià)格：￥3600/￥2500
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其他：
產(chǎn)品詳情
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產(chǎn)品描述：大鼠α1微球蛋白/bikunin蛋白前體(AMBP)酶聯(lián)免疫試劑盒（CSB-EL001654RA）為競(jìng)爭(zhēng)法ELISA試劑盒，定量檢測(cè)血清、血漿、組織勻漿樣本中的AMBP含量。試劑盒檢測(cè)范圍為1.563 ng/mL-100 ng/mL，靈敏度為0.649 ng/mL。為科研領(lǐng)域研究AMBP在代謝性疾病模型、組織損傷修復(fù)機(jī)制或藥物干預(yù)效果評(píng)估中的動(dòng)態(tài)變化提供可靠工具，尤其適用于動(dòng)物實(shí)驗(yàn)中的生物標(biāo)志物探索及分子通路機(jī)制解析本品僅用于科研，不用于臨床診斷，產(chǎn)品具體參數(shù)及操作步驟詳見(jiàn)產(chǎn)品說(shuō)明書(shū)。
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別名：Ambp ELISA Kit; ItilProtein AMBP [Cleaved into: Alpha-1-microglobulin; Inter-alpha-trypsin inhibitor light chain ELISA Kit; ITI-LC ELISA Kit; Bikunin ELISA Kit; HI-30); Trypstatin] ELISA Kit
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縮寫(xiě)：AMBP
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Uniprot No.：
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種屬：Rattus norvegicus (Rat)
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樣本類(lèi)型：serum, plasma, tissue homogenates
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檢測(cè)范圍：1.563 ng/mL-100 ng/mL
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靈敏度：0.649 ng/mL
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反應(yīng)時(shí)間：1-5h
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樣本體積：50-100ul
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檢測(cè)波長(zhǎng)：450 nm
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研究領(lǐng)域：Cancer
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測(cè)定原理：quantitative
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測(cè)定方法：Competitive
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精密度：
Intra-assay Precision (Precision within an assay): CV%<8% Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV%<10% Three samples of known concentration were tested in twenty assays to assess. -
線性度：
To assess the linearity of the assay, samples were spiked with high concentrations of rat AMBP in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay. Sample Serum(n=4) 1:100 Average % 105 Range % 99-109 1:200 Average % 96 Range % 92-99 1:400 Average % 95 Range % 90-98 1:800 Average % 89 Range % 84-94 -
回收率：
The recovery of rat AMBP spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section. Sample Type Average % Recovery Range Serum (n=5) 91 87-95 EDTA plasma (n=4) 99 99-104 -
標(biāo)準(zhǔn)曲線：
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed. 
ng/ml OD1 OD2 Average 100 0.116 0.124 0.120 50 0.231 0.245 0.238 25 0.478 0.498 0.488 12.5 1.019 1.025 1.022 6.25 1.426 1.367 1.397 3.125 2.159 2.168 2.164 1.563 2.466 2.544 2.505 0 2.845 2.654 2.750 -
數(shù)據(jù)處理：
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貨期：3-5 working days
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相關(guān)產(chǎn)品
靶點(diǎn)詳情
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最新研究進(jìn)展：AMBP（α1酸性糖蛋白）是一種由肝臟合成的糖蛋白，具有多種生物學(xué)功能，包括與免疫系統(tǒng)、炎癥反應(yīng)和病原體識(shí)別相關(guān)。最近的研究表明，AMBP在多種疾病中發(fā)揮著重要作用，例如腎臟疾病、肝病、癌癥、糖尿病、心血管疾病等。以下是AMBP的最新研究進(jìn)展：腎臟疾病：AMBP被認(rèn)為是腎臟疾病的標(biāo)志物之一，其水平與腎小球?yàn)V過(guò)率、尿蛋白和炎癥反應(yīng)相關(guān)。最近的研究還發(fā)現(xiàn)，AMBP可以作為腎小球腎炎的標(biāo)志物，有助于診斷和監(jiān)測(cè)該疾病的進(jìn)展。癌癥：AMBP的水平在多種癌癥中明顯升高，包括肝癌、胃癌、肺癌等。最近的研究表明，AMBP可能參與了腫瘤的發(fā)生、發(fā)展和轉(zhuǎn)移，并且可以作為癌癥的潛在治療靶點(diǎn)。免疫系統(tǒng)：AMBP可以通過(guò)多種方式參與免疫系統(tǒng)調(diào)節(jié)，包括識(shí)別和清除病原體、調(diào)節(jié)T細(xì)胞和B細(xì)胞功能、參與炎癥反應(yīng)等。最近的研究表明，AMBP在免疫系統(tǒng)調(diào)節(jié)中的作用可能是通過(guò)與其他分子相互作用，如IgG、Toll樣受體（TLR）等。
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功能：Inter-alpha-trypsin inhibitor inhibits trypsin, plasmin, and lysosomal granulocytic elastase. Inhibits calcium oxalate crystallization.; Trypstatin is a trypsin inhibitor. It inhibits blood coagulation factor Xa and tryptase about 100-fold more rapidly than porcine pancreatic trypsin and chymase.
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亞細(xì)胞定位：Secreted.
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蛋白家族：Calycin superfamily, Lipocalin family
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組織特異性：Expressed by the liver and secreted in plasma. Alpha-1-microglobulin occurs in many physiological fluids including plasma, urine, and cerebrospinal fluid. Inter-alpha-trypsin inhibitor is present in plasma and urine. Trypstatin is present in mast cell gra
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