Rat adiponectin,ADP ELISA Kit

文獻引用 (33) 說明書下載

中文名稱：

大鼠脂聯素(ADP)酶聯免疫試劑盒
貨號：

CSB-E07271r
規(guī)格：

96T/48T
價格：

￥3900/￥2500
其他：

CUSABIO Wins 2024 Bioz Rapid Star? Award in the ELISA category

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產品描述：

大鼠脂聯素(ADP)酶聯免疫試劑盒（CSB-E07271r）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿、組織培養(yǎng)上清液、組織勻漿樣本中的ADP含量。ADP即二磷酸腺苷，在生物體內能量代謝中扮演關鍵角色。其與血小板表面受體結合可誘導血小板活化和聚集。目前研究聚焦于以ADP為靶點，開發(fā)抗血小板藥物，通過阻斷其相關信號通路，抑制血小板功能，預防和治療血栓性疾病。試劑盒檢測范圍為0.156 ng/mL-10 ng/mL，靈敏度為0.039 ng/mL。適用于代謝調控機制研究、藥物干預效果評估或疾病模型構建等科研領域，為探索脂聯素在能量代謝、炎癥反應及胰島素抵抗中的作用提供可靠工具本品僅用于科研，不用于臨床診斷，產品具體參數及操作步驟詳見產品說明書。
縮寫：

ADP
Uniprot No.：

Q8K3R4
種屬：

Rattus norvegicus (Rat)
樣本類型：

serum, plasma, cell culture supernates, tissue homogenates
檢測范圍：

0.156 ng/mL-10 ng/mL
靈敏度：

0.039 ng/mL
反應時間：

1-5h
樣本體積：

50-100ul
檢測波長：

450 nm
研究領域：

Cardiovascular
測定原理：

quantitative
測定方法：

Sandwich
精密度：

Intra-assay Precision (Precision within an assay): CV%<8%

Three samples of known concentration were tested twenty times on one plate to assess.

Inter-assay Precision (Precision between assays): CV%<10%

Three samples of known concentration were tested in twenty assays to assess.
線性度：

To assess the linearity of the assay, samples were spiked with hig3h concentrations of rat ADP in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
標準曲線：

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
數據處理：

ELISA操作視頻及標曲繪制軟件下載
貨期：

3-5 working days

引用文獻

The effect of adipose-derived mesenchymal stem cells against high fructose diet induced liver dysfunction and dysbiosis MA Mohammed, NHA Hay, MT Mohammed,Naunyn-Schmiedeberg's Archives of Pharmacology,2024
Unraveling the hepatic stellate cells mediated mechanisms in aging's influence on liver fibrosis RM Wahid,Scientific reports,2024
Regulation and Role of Adiponectin Secretion in Rat Ovarian Granulosa Cells Y Zhou,International Journal of Molecular Sciences,2024
The ameliorative role of germinated fenugreek and barley grains on the structure and function of offspring's tibialis muscle maternally fed on high fat diet FA Hassan Megahed,/,2024
The Potential Efficacy of Artemisia Anuua L. Extract Nanoparticles in Mitigating Obesity-Related-Metabolic Complications in Hypercaloric Diet-Fed Rats MM Mohameda,/,2023
The potential efficacy of Artemisia anuua L. extract nanoparticles in mitigating obesity-related-metabolic complications in hypercaloric diet-fed rats MM Mohamed,/,2024
A novel role of FSH on regulating ovarian adiponectin expression in rat ovarian granulosa cells Y Zhou,researchsquare,2023
Enhancement of biochemical and genomic pathways through lycopene-loaded nano-liposomes: Alleviating insulin resistance, hepatic steatosis, and autophagy in obese rats with non-alcoholic fatty liver disease: Involvement of SMO, GLI-1, and PTCH-1 genes GA Salem,Gene,2023
Quinoa and Chia Modulate AMPK/PPAR-? Signaling in High-Fat Diet–Induced Obesity Rat Model NH Omran,Revista Brasileira de Farmacognosia,2023
Cytokine modulation by etanercept ameliorates metabolic syndrome and its related complications induced in rats administered a high-fat high-fructose diet NF Hassan,Scientific reports,2022
Indapamide Increases IRS1 Expression and Modifies Adiponectin/NLRP3/PPARγ Crosstalk in Type 2 Diabetic Rats MM Samaha,Antioxidants (Basel, Switzerland),2022
Diacerein versus adipoRon as adiponectin modulators in experimentally-induced end-stage type 2 diabetes mellitus in rats MM Samaha,Environmental toxicology and pharmacology,2022
Saponin-rich extract of Tribulus terrestris alleviates systemic inflammation and insulin resistance in dietary obese female rats: Impact on adipokine/hormonal disturbances YousraAbdel-Mottaleb,Biomedicine & pharmacotherapy,2022
The metabolic impact and beneficial effects of different energy restriction protocols in rats: an alternative health plan K El-Dawy,Journal of Animal Health and Production,2021
Irradiation of carotid baroreceptor with low‐intensity pulsed ultrasound exerts different metabolic protection in perirenal, epididymal white adipose tissue and interscapular brown adipose tissue of obese rats Q Cao,FASEB J,2020
Beneficial phytoestrogenic effects of resveratrol on polycystic ovary syndromein rat model N Zhang,Journal Gynecological Endocrinology,2020
Alagebrium Mitigates Metabolic Insults in High Carbohydrate and High Fat Diet Fed Wistar Rats S Hassan,Pharmaceutical Sciences,2020
Anti-depressive effects of Kai-Xin-San on lipid metabolism in depressed patients and CUMS rats using metabolomic analysis X Zhou,Journal of Ethnopharmacology,2020
Lansoprazole enhances the antidiabetic effect of dapagliflozin in fortified diet┸\fed streptozotocin┸\treated diabetic rats Noha M. Gamil,J. Biochem. Mol. Toxicol,2020
Experimental hypothyroidism in adult male rats: the effects of Artemisia dracunculus aqueous extract on serum thyroid hormones, lipid profile, leptin, adiponectin, and antioxidant factors Mohammadi M M, et al,Comparative Clinical Pathology,2019
Alagebrium Mitigates Metabolic Insults in High Carbohydrate High Fat Diet Fed Rats Hady S H A, et al,Pharmaceutical Sciences,2019
Grinding levels of raspberry pomace affect intestinal microbial activity, lipid and glucose metabolism in Wistar rats BartoszFotschk, et al,Food research international,2019
Alpha lipoic acid protects against dexamethasone-induced metabolic abnormalities via APPL1 and PGC-1 α up regulation Mohammed MA, et al,Steroids,2019
High Fat/High Glucose Diet Induces Metabolic Syndrome in an Experimental Rat Model Moreno-Fernandez S.et al,Nutrients,2018
Protective Effects of Ellagitannin-Rich Strawberry Extracts on Biochemical and Metabolic Disturbances in Rats Fed a Diet High in Fructose Bartosz Fotschki .et al,Nutrients,2018
A combination of quercetin and resveratrol reduces obesity in high-fat diet-fed rats by modulation of gut microbiota Zhao L.et al,Food Funct.,2017
Tetradecyl 2,3-Dihydroxybenzoate Improves the Symptoms of Diabetic Mice by Modulation of Insulin and Adiponectin Signaling Pathways Lan Xiang.et al,Front. Pharmacol,2017
Pepsin egg white hydrolysate ameliorates metabolic syndrome in high-fat/high-dextrose fed rats Silvia Moreno-Fernndez.et al,Food & Function,2017
Anti-diabetic effects of soluble and insoluble dietary fibre from deoiled cumin in low-dose streptozotocin and high glucose-fat diet-induced type 2 diabetic rats Ma M.et al, Journal of Functional Foods,2016
Glycyrrhizic acid prevents high calorie diet-induced metabolic aberrations despite the suppression of peroxisome proliferator-activated receptor 緯 expression Hong Sheng Cheng.et al,Nutrition,2016
Fish oil supplementation alleviates depressant-like behaviors and modulates lipid profiles in rats exposed to chronic unpredictable mild stress Tang M.et al,BMC Complement Altern Med.,2015
Comparison of the anti-obesity and hypocholesterolaemic effects of single Lactobacillus casei strain Shirota and probiotic cocktail Shafiq Aazmi et al,Food Science & Technology,2015
CD40L Deficiency Attenuates Diet-Induced Adipose Tissue Inflammation by Impairing Immune Cell Accumulation and production of pathogenic IgG-antibodies Dennis Wolf et al,PLOS ONE,2012

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最新研究進展：

近年來，脂聯素（Adiponectin，ADP）作為一種由脂肪組織分泌的激素，受到了廣泛關注。ADP對人體的代謝、炎癥反應和心血管健康等生理過程均具有重要的作用。最新的研究發(fā)現，ADP在以下幾個方面具有突出的研究進展：
代謝調節(jié)：研究表明，ADP可以調節(jié)人體的葡萄糖代謝和脂質代謝，降低胰島素抵抗和脂肪肝的發(fā)生，對代謝綜合征和肥胖等代謝性疾病的治療具有潛在作用。

炎癥調節(jié)：ADP也在炎癥反應中發(fā)揮重要作用。研究發(fā)現，ADP可以抑制炎癥介質的產生和釋放，調節(jié)免疫細胞的活化和凋亡，對于炎癥反應和自身免疫性疾病的治療具有一定的潛力。

心血管保護：ADP能夠降低血壓和血脂，預防動脈粥樣硬化和心血管疾病的發(fā)生。此外，ADP還能夠減輕心肌損傷和缺血再灌注損傷。

腫瘤治療：ADP在腫瘤治療中也備受關注。研究發(fā)現，ADP可以影響腫瘤細胞的增殖、侵襲和轉移，對于腫瘤的治療和預防具有潛在作用。

總之，ADP作為一種重要的激素，其在代謝、炎癥、心血管和腫瘤等多個生理和病理過程中的作用引起了廣泛關注，對于相關疾病的治療和預防具有重要的臨床應用前景。

Rat adiponectin,ADP ELISA Kit

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