-
中文名稱：大鼠前列腺素E2(PGE2)酶聯免疫試劑盒
-
貨號：CSB-E07967r
-
規格：96T/48T
-
價格：￥3200/￥2500
-
其他：
產品詳情
-
產品描述：大鼠前列腺素E2(PGE2)酶聯免疫試劑盒（CSB-E07967r）為競爭法ELISA試劑盒，定量檢測血清、血漿、組織勻漿、細胞裂解物樣本中的PG-E2含量。PG-E2即前列腺素E2，它在體內廣泛存在，參與多種生理和病理過程。在炎癥、免疫調節、腫瘤發生發展等方面扮演重要角色。研究機制主要圍繞其與受體結合，激活多條信號通路，影響細胞增殖、分化和炎癥因子釋放等過程。試劑盒檢測范圍為0.5 pg/mL-100 pg/mL，適用于體外實驗研究，例如探究炎癥模型中PGE2的動態變化、評估藥物或化合物對前列腺素代謝通路的影響，以及組織微環境中脂質介質的定量分析等科研場景，為炎癥機制研究、藥效學評價及生物標志物探索提供高效檢測工具。本品僅用于科研，不用于臨床診斷，產品具體參數及操作步驟詳見產品說明書。
-
縮寫：PG-E2
-
種屬：Rattus norvegicus (Rat)
-
樣本類型：serum, plasma, tissue homogenates, cell lysates
-
檢測范圍：0.5 pg/mL-100 pg/mL
-
靈敏度：0.25 pg/mL
-
反應時間：1-5h
-
樣本體積：50-100ul
-
檢測波長：450 nm
-
研究領域：Signal Transduction
-
測定原理：quantitative
-
測定方法：Competitive
-
精密度：
Intra-assay Precision (Precision within an assay): CV%<15% Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV%<15% Three samples of known concentration were tested in twenty assays to assess. -
線性度：
To assess the linearity of the assay, samples were spiked with high concentrations of rat PG-E2 in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay. Sample Serum(n=4) 1:1 Average % 96 Range % 91-99 1:2 Average % 92 Range % 87-96 1:4 Average % 93 Range % 89-98 1:8 Average % 105 Range % 99-109 -
回收率：
The recovery of rat PG-E2 spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section. Sample Type Average % Recovery Range Serum (n=5) 96 92-99 EDTA plasma (n=4) 101 96-104 -
標準曲線：
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed. 
pg/ml OD1 OD2 Average 100 0.228 0.224 0.226 25 0.365 0.348 0.357 8 0.560 0.539 0.550 2 0.813 0.787 0.800 0.5 1.258 1.234 1.246 0 2.031 2.176 2.104 -
數據處理：
-
貨期：3-5 working days
引用文獻
- Pharmacodynamic Study of Gubi granules in the Treatment of Osteoarthritis Y Bao, L Hao, Y Liao, J Sun, Y Chen, J Li, H Li,Pharmacological Research-Modern Chinese Medicine,2025
- Eucalyptol Attenuates Indomethacin-Induced Gastric Ulcers in Rats by Modulating the ICAM-1, eNOS and COX/LOX Pathways: Insights from In Silico, In Vitro and In Vivo Approaches U Iqbal, A Malik, NT Sial, MH Mehmood,Food and Chemical Toxicology,2025
- Pinus densiflora Root Extract Attenuates Osteoarthritis Progression by Inhibiting Inflammation and Cartilage Degradation in Interleukin-1β and Monosodium Iodoacetate-Induced Osteoarthritis Models YM Park, DY Shin, HY Lee, HM Hwang, JG Kim,Nutrients,2024
- Cannabigerol as an anti-inflammatory agent altering the level of arachidonic acid derivatives in the colon tissue of rats subjected to a high-fat high-sucrose diet K Sztolsztener, E Harasim-Symbor,Biomedicine & Pharmacotherapy,2024
- N-acetylcysteine acts as a potent anti-inflammatory agent altering the eicosanoid profile in the development of simple steatosis and its progression to hepatitis K Sztolsztener,/,2023
- Arbutin attenuates CFA-induced Arthritis by modulating expression levels of 5-LOX, NF-κB, IL-17, PGE-2 and TNF-α A Malik,researchsquare,2023
- α-Lipoic acid–A promising agent for attenuating inflammation and preventing steatohepatitis in rats fed a high-fat diet M Zwierz,Archives of biochemistry and biophysics,2023
- Thymol ameliorates 5‐fluorouracil‐induced intestinal mucositis: Evidence of down‐regulatory effect on TGF‐β/MAPK pathways through NF‐κB LA Al‐Khrashi,Journal of biochemical and molecular toxicology,2023
- Inhibition of 15‐hydroxyprostaglandin dehydrogenase protects neurons from ferroptosis in ischemic stroke HA Hamouda,MedComm,2024
- The Effect of the Mixed Extract of Kalopanax pictus Nakai and Achyranthes japonica Nakai on the Improvement of Degenerative Osteoarthritis through Inflammation Inhibition in the Monosodium Iodoacetate-Induced Mouse Model HY Lee,Current Issues in Molecular Biology,2023
- Therapeutic effect of cannabidiol on myocardial arachidonic acid content in various lipid fractions in a rat model of obesity K Sztolsztener,Prostaglandins & other lipid mediators,2023
- Baroreflex Sensitivity, Cardiac and Kidney Remodeling and Deterioration in Vasoactive Substances Content in Blood in Experimental Model of Renovascular Hypertension. Action of Natural Flavone, Luteolin NA Papiashvili,Journal of Nephrology Advances-1 (4),2023
- Plausibility of Daphnia magna as an alternative experimental model to evaluate effects on eicosanoid synthesis S Lee,Ecotoxicology and environmental safety,2023
- Modulatory Activity of Aju Mbaise Polyherbal Formulation on Serum Proinflammatory Cytokines and Prostaglandin Levels in Nulliparous and Parturient Female Albino Rats VK Agu,Journal of Complementary and Alternative Medical Research,2023
- The neuroprotective effect of pterostilbene on oxaliplatin-induced peripheral neuropathy via its anti-inflammatory, anti-oxidative and anti-apoptotic effects: Comparative study with celecoxib MA Abd-Elmawla,Life sciences,2023
- Zerumbone Protects Rats from Collagen-Induced Arthritis by Inhibiting Oxidative Outbursts and Inflammatory Cytokine Levels RM Alsaffar,ACS publications,2023
- Gastroprotective effect of dapagliflozin in ethanol-induced gastric lesions in rats: Crosstalk between HMGB1/RAGE/PTX3 and TLR4/MyD88/VEGF/PDGF signaling pathways RM Salama,International immunopharmacology,2023
- Plasma prostaglandin levels and expression in sacroiliac joints: Effects of low swim training in pregnant rats I Oktaviani,AIP Conference Proceedings,2022
- Toxic effects of excess exposure to boric acid on serum biochemical aspect, hematology and histological alterations and ameliorative potential role of melatonin in rats HTH Ismail,Saudi journal of biological sciences,2022
- Assessment of the Potential of Sarcandra glabra (Thunb.) Nakai. in Treating Ethanol-Induced Gastric Ulcer in Rats Based on Metabolomics and Network Analysis Chao Li,Frontiers in pharmacology,2022
- Anti-Inflammatory Activity of Essential Oil from Zingiber ottensii Valeton in Animal Models W Thitinarongwate,Molecules,2022
- Piceatannol Affects Gastric Ulcers Induced by Indomethacin: Association of Antioxidant, Anti-Inflammatory, and Angiogenesis Mechanisms in Rats RA Shaik,Life,2022
- MiR-34a-5p up-regulates the IL-1β/COX2/PGE2 inflammation pathway and induces the release of CGRP via inhibition of SIRT1 in rat trigeminal ganglion neurons. H Zhang,FEBS Open Bio,2020
- Physiological and Histopathological Effects of Electroporation Pulse on Stomach of Rats Y Zhang,BMC Gastroenterology,2020
- Gastroprotective effect of Lycium barbarum polysaccharides and C-phyocyanin in rats with ethanol-induced gastric ulcer YZ Lian,International Journal of Biological Macromolecules,2020
- Regulation of PGE2 Pathway During Cerebral Ischemia Reperfusion Injury in Rat Y Xu,Cell. Mol. Neurobiol,2020
- Resveratrol-loaded biopolymer core-shell nanoparticles: Bioavailability and anti-inflammatory effects Y Liu,Food Funct.,2020
- Two Neoflavones from Aconitum Austroyunnanense and their Therapeutic Activity Against Osteoarthritis of the Knee Z Xu,Chemistry of Natural Compounds volume,2020
- Seasonal expressions of prostaglandin E synthases and receptors in the prostate of the wild ground squirrel (Spermophilus dauricus) Chen Z,Prostaglandins Other Lipid Mediat,2020
- Anti-inflammatory Action of YHQ by Regulating 5-LOX/COX-2/NF-κB/MAPKs/Akt Signaling Pathways in RAW 264.7 Macrophage cells Hu TY, et al,Journal of Herbal Medicine,2019
- Anti-inflammation Action of Xanthones from Swertia chirayita by Regulating COX-2/NF-κB/MAPKs/Akt Signaling Pathways in RAW 264.7 Macrophage cells Tian-Yong Hu .et al,Phytomedicine,2018
- Ginsenoside metabolite compound K exerts anti-inflammatory and analgesic effects via downregulating COX2 Jingyu Chen.et al,Inflammopharmacology,2018
- Gastro protective Effect of Pentagalloyl Glucose on Aspirin Induced Gastric Mucosal Ulcer in Comparison with Omeprazole, Famotidine and Melatonin Moharram.et al,Journal of Pharmaceutical Sciences and Research,2017
- Enhanced lipoxygenase/LTD4 signaling accounts for the exaggerated hypertensive and nephrotoxic effects of cyclosporine plus indomethacin in rats Helmy MW.et al,Biomedicine & Pharmacotherapy,2018
- Protective effect of coptisine free base on indomethacin-induced gastric ulcers in rats: Characterization of potential molecular mechanisms Luo C.et al,Life Sci,2017
- Quercetin attenuates collagen-induced arthritis by restoration of Th17/Treg balance and activation of Heme Oxygenase 1-mediated anti-inflammatory effect Yang Y.et al,Int Immunopharmacol,2017
- Therapeutic effects of Qian-Yu decoction and its three extracts on carrageenan-induced chronic prostatitis/chronic pelvic pain syndrome in rats Keda Zhang.et al,BMC Complementary and Alternative Medicine,2017
- Use of a balanced dual cyclooxygenase-1/2 and 5-lypoxygenase inhibitor in experimental colitis. Pallio G.et al,Eur J Pharmacol.,2016
- The expression of prostaglandin-E2 and its receptor in the oviduct of Chinese brown frog (Rana dybowskii). Hu R.et al,Prostaglandins Other Lipid Mediat.,2016
- Regulation of the secretion of immunoregulatory factors of mesenchymal stem cells (MSCs) by collagen-based scaffolds during chondrogenesis Yang J.et al,Materials Science and Engineering: C,2016
- Nebivolol prevents indomethacin-induced gastric ulcer in rats. El-Ashmawy NE.et al,J Immunotoxicol.,2016
- Comparative pharmaceutical study on colon targeted micro-particles of celecoxib: in-vitro-in-vivo evaluation. Bazan L.et al,Drug Deliv.,2016
- Anti-inflammatory and antipyretic properties of Kang 601 heji, a traditional Chinese oral liquid dosage form Raphael Nammahime Alolga.et al,Asian Pacific Journal of Tropical Biomedicine,2015
- Geraniol ameliorates TNBS-induced colitis: Involvement of Wnt/ß-catenin, p38MAPK, NFkB, and PPARr signaling pathways Soubh AA. et al,Life Sci,2015
- Rhizoma Paridis Saponins Suppresses Tumor Growth in a Rat Model of N-Nitrosomethylbenzylamine-Induced Esophageal Cancer by Inhibiting Cyclooxygenases-2 Pathway. Yan S. et al,PLoS One,2015
- Reduction of spinal PGE 2 concentrations prevents swim stress-induced thermal hyperalgesia Guevara C et al,Neurosci Lett,2015
- Evaluation of the Effects of Caffeic Acid Phenethyl Ester on Prostaglandin E2 and Two Key Cytokines Involved in Bleomycin-induced Pulmonary Fibrosis Larki-Harchegani A et al,Iran J Basic Med Sci,2013
- Anti-inflammatory and Anti-oxidant Activities of Olmesartan Medoxomil Ameliorate Experimental Colitis in Rats Marwa M. Nagib et al,Toxicology and Applied Pharmacology,2013
- Mechanisms underlining gender differences in Phenylephrine contraction of normoglycaemic and short-term Streptozotocin-induced diabetic WKY rat aorta U.I. Aloysius et al,Brain Research,2012
產品評價
平均分:
樣品類型：血清
樣品信息：大鼠
稀釋比：沒有稀釋
產品評價： 檢測pg-e2在血清中的含量，該試劑盒操作較方便，已經備好六只標準品，自行配液誤差較小，從實驗結果可以看出效果較好，希望其他試劑盒也能配好標準品，盡量減少操作可能出現誤差，簡化流程
By 李老師
相關產品
靶點詳情
-
最新研究進展：PGE2是一種前列腺素，與炎癥和癌癥等多種疾病有關。近期的研究表明，PGE2可以在體內誘導肝癌干細胞分化為肝癌細胞，從而促進肝癌的發生和發展。此外，研究人員還發現，通過靶向PGE2的合成酶和受體可以減少腫瘤的生長和轉移，從而為腫瘤治療提供新的策略。
Most popular with customers
-
Human Transforming Growth factor β1,TGF-β1 ELISA kit
Detect Range: 23.5 pg/ml-1500 pg/ml
Sensitivity: 5.8 pg/ml
-
-
-
Mouse Tumor necrosis factor α,TNF-α ELISA Kit
Detect Range: 7.8 pg/ml-500 pg/ml
Sensitivity: 1.95 pg/ml
-
-
-
-
