Mouse C-X-C motif chemokine 3(CXCL3) ELISA kit
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中文名稱：小鼠C-X-C趨化因子3(CXCL3)酶聯(lián)免疫試劑盒
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貨號：CSB-EL006249MO
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規(guī)格：96T/48T
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價格：￥3600/￥2500
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其他：
產(chǎn)品詳情
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產(chǎn)品描述：小鼠C-X-C趨化因子3(CXCL3)酶聯(lián)免疫試劑盒（CSB-EL006249MO）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿、組織勻漿樣本中的CXCL3含量。CXCL3作為一個靶點，其屬于趨化因子家族。背景上在炎癥等生理病理過程中發(fā)揮作用。研究機制方面，它能與相應(yīng)受體結(jié)合，介導(dǎo)細胞遷移和活化，參與免疫反應(yīng)調(diào)節(jié)，在腫瘤、自身免疫病等發(fā)病機制研究中有重要意義。試劑盒檢測范圍為7.8 pg/mL-500 pg/mL，適用于基礎(chǔ)科研領(lǐng)域，例如通過分析CXCL3在小鼠感染模型、自身免疫性疾病模型或腫瘤移植模型中的動態(tài)變化，探究其與中性粒細胞募集、血管生成或免疫逃逸等過程的關(guān)聯(lián)機制。支持科研人員高效開展CXCL3相關(guān)分子機制研究及生物標(biāo)志物探索。本品僅用于科研，不用于臨床診斷，產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
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別名：Cxcl3 ELISA Kit; Dcip1 ELISA Kit; Gm1960C-X-C motif chemokine 3 ELISA Kit; Dendritic cell inflammatory protein 1 ELISA Kit
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縮寫：
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Uniprot No.：
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種屬：Mus musculus (Mouse)
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樣本類型：serum, plasma, tissue homogenates
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檢測范圍：7.8 pg/mL-500 pg/mL
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靈敏度：1.56 pg/mL
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反應(yīng)時間：1-5h
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樣本體積：50-100ul
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檢測波長：450 nm
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研究領(lǐng)域：Immunology
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測定原理：quantitative
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測定方法：Sandwich
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精密度：
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線性度：
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回收率：
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標(biāo)準(zhǔn)曲線：
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數(shù)據(jù)處理：
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貨期：3-5 working days
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點詳情
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功能：Ligand for CXCR2. Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion.
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基因功能參考文獻：
- The studies revealed that, although overall structural and oligomerization features of CXCL3 and CXCL2 are similar, prominent differences were observed in their surface characteristics, thus implicating a functional divergence. PMID: 28928065
- these results have indicated that CXCL3 is a novel adipokine that facilitates adipogenesis in an autocrine and/or a paracrine manner through induction of c/ebpb and c/ebpd. PMID: 27512010
- Tis21 induces migration of cerebellar granule neuron precursor cells through Cxcl3, which may represent a novel target for medulloblastoma therapy PMID: 23115191
- DCIP-1 interacts with chemokine CXCR2 and mediates human neutrophil chemotaxis, consistent with its role during the early proinflammatory phase of dendritic cell maturation. PMID: 14764687
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亞細胞定位：Secreted.
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蛋白家族：Intercrine alpha (chemokine CxC) family
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數(shù)據(jù)庫鏈接：
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