Human Platelet-Derived Growth Factor-BB,PDGF-BB ELISA kit

文獻(xiàn)引用 (7) 說明書下載

中文名稱：

人血小板衍生生長因子BB(PDGF-BB)酶聯(lián)免疫試劑盒
貨號：

CSB-E08923h
規(guī)格：

96T/48T
價(jià)格：

￥3200/￥2500
其他：

CUSABIO Wins 2024 Bioz Rapid Star? Award in the ELISA category

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產(chǎn)品描述：

人血小板衍生生長因子BB(PDGF-BB)酶聯(lián)免疫試劑盒（CSB-E08923h）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿、組織勻漿樣本中的PDGF-BB含量。PDGF-BB 是血小板衍生生長因子的一種亞型，在細(xì)胞的生長、增殖和遷移等過程中發(fā)揮重要作用。其異常表達(dá)與腫瘤生長、血管生成、纖維化疾病等密切相關(guān)。研究聚焦于其信號通路機(jī)制，旨在開發(fā)針對性藥物干預(yù)，以治療相關(guān)疾病。試劑盒檢測范圍為31.25 pg/mL-2000 pg/mL，靈敏度為7.81 pg/mL。可為心血管疾病機(jī)制研究、抗纖維化藥物開發(fā)、腫瘤微環(huán)境分析等基礎(chǔ)科研提供定量數(shù)據(jù)支持本品僅用于科研，不用于臨床診斷，產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
縮寫：

PDGF-BB
種屬：

Homo sapiens (Human)
樣本類型：

serum, plasma, tissue homogenates
檢測范圍：

31.25 pg/mL-2000 pg/mL
靈敏度：

7.81 pg/mL
反應(yīng)時(shí)間：

1-5h
樣本體積：

50-100ul
檢測波長：

450 nm
研究領(lǐng)域：

Cardiovascular
測定原理：

quantitative
測定方法：

Sandwich
精密度：

Intra-assay Precision (Precision within an assay): CV%<8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV%<10%
Three samples of known concentration were tested in twenty assays to assess.
線性度：

To assess the linearity of the assay, samples were spiked with high concentrations of human PDGF-BB in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
回收率：

The recovery of human PDGF-BB spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
標(biāo)準(zhǔn)曲線：

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
數(shù)據(jù)處理：

ELISA操作視頻及標(biāo)曲繪制軟件下載
貨期：

3-5 working days

引用文獻(xiàn)

VALUTAZIONE DELL'UTILIZZO DEL LISATO PIASTRINICO (LP) IN MEDICINA RIGENERATIVA VETERINARIA EDE DELLA LOMBARDIA,/,2023
The use of human‐derived feeder layers for the cultivation of transplantable human epidermal cell sheet to repair second degree burn wounds Z Mingqi,Skin research and technology,2023
Platelet Activation Favours NOX2-Mediated Muscle Damage in Elite Athletes: The Role of Cocoa-Derived Polyphenols A D'Amico,Nutrients,2022
Small-Dose Sunitinib Modulates p53, Bcl-2, STAT3, and ERK1/2 Pathways and Protects against Adenine-Induced Nephrotoxicity MA Saleh,Pharmaceuticals (Basel),2020
Biological Effects of a Three-Dimensionally Printed Ti6Al4V Scaffold Coated with Piezoelectric BaTiO3 Nanoparticles on Bone Formation W Liu,ACS Applied Materials & Interfaces,2020
Reduced Platelet miR-223 Induction in Kawasaki Disease Leads To Severe Coronary Artery Pathology Through a miR-223/PDGFRβ Vascular Smooth Muscle Cell Axis Yuan Zhang,CIRCULATION RESEARCH,2020
Low temperature plasma induces angiogenic growth factor via up-regulating hypoxia?inducible factor 1α in human dermal fibroblasts Hui SongCui.et al,Archives of Biochemistry and Biophysics,2017

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最新研究進(jìn)展：

PDGF-BB是血小板源性生長因子（platelet-derived growth factor，PDGF）家族的一個(gè)亞型，由PDGF-B兩個(gè)亞基組成。最近的研究表明，PDGF-BB參與了多種生物學(xué)過程，如細(xì)胞增殖、分化、遷移和細(xì)胞外基質(zhì)合成等。此外，PDGF-BB在多種疾病中也發(fā)揮著重要作用，如腫瘤、動脈粥樣硬化和組織損傷等。因此，PDGF-BB成為了治療靶點(diǎn)的研究熱點(diǎn)。一些研究已經(jīng)探索了PDGF-BB的抑制劑和抗體，以期望發(fā)現(xiàn)更有效的治療方案。

Human Platelet-Derived Growth Factor-BB,PDGF-BB ELISA kit

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