Human Arachidonic Acid,AA ELISA Kit
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中文名稱(chēng)：人花生四烯酸(AA)酶聯(lián)免疫試劑盒
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貨號(hào)：CSB-E09040h
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規(guī)格：96T/48T
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價(jià)格：￥3600/￥2500
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其他：
產(chǎn)品詳情
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產(chǎn)品描述：人花生四烯酸(AA)酶聯(lián)免疫試劑盒（CSB-E09040h）為競(jìng)爭(zhēng)法ELISA試劑盒，定量檢測(cè)血清、血漿、組織培養(yǎng)上清液、組織勻漿樣本中的AA含量。花生四烯酸（AA）是一種必需脂肪酸，其代謝產(chǎn)物在炎癥、免疫和神經(jīng)系統(tǒng)功能中起關(guān)鍵作用。AA通過(guò)環(huán)氧化酶（COX）和脂氧合酶（LOX）途徑轉(zhuǎn)化為前列腺素和白三烯等生物活性分子，這些分子在多種疾病如癌癥、炎癥和心血管疾病中扮演重要角色。研究AA的代謝途徑和靶點(diǎn)對(duì)于開(kāi)發(fā)治療這些疾病的新療法具有重要意義。試劑盒檢測(cè)范圍為78.125 ng/mL-5000 ng/mL，靈敏度為69.748 ng/mL。適用于基礎(chǔ)科研中炎癥機(jī)制研究、脂質(zhì)代謝調(diào)控實(shí)驗(yàn)、藥物或營(yíng)養(yǎng)干預(yù)對(duì)AA通路影響的評(píng)估，以及細(xì)胞模型中AA釋放水平的動(dòng)態(tài)監(jiān)測(cè)。該檢測(cè)體系可為探索AA在心血管疾病、神經(jīng)退行性疾病等病理生理過(guò)程中的作用提供可靠工具。本品僅用于科研，不用于臨床診斷，產(chǎn)品具體參數(shù)及操作步驟詳見(jiàn)產(chǎn)品說(shuō)明書(shū)。
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別名：N/A
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縮寫(xiě)：AA
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種屬：Homo sapiens (Human)
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樣本類(lèi)型：serum, plasma, cell culture supernates, tissue homogenates
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檢測(cè)范圍：78.125 ng/mL-5000 ng/mL
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靈敏度：69.748 ng/mL
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反應(yīng)時(shí)間：1-5h
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樣本體積：50-100ul
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檢測(cè)波長(zhǎng)：450 nm
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研究領(lǐng)域：Biochemicals
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測(cè)定原理：quantitative
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測(cè)定方法：Competitive
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精密度：
Intra-assay Precision (Precision within an assay): CV%<8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV%<10%
Three samples of known concentration were tested in twenty assays to assess.
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線性度：
To assess the linearity of the assay, samples were spiked with high concentrations of human AA in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
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標(biāo)準(zhǔn)曲線：
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
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數(shù)據(jù)處理：
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貨期：3-5 working days
引用文獻(xiàn)
- Essential roles of exosome and circRNA_101093 on ferroptosis desensitization in lung adenocarcinoma X Zhang,Cancer communications,2023
- Aqueous Extract of Tournefortia sarmentosa Stem Inhibits ADP-induced Platelet Aggregation Wang, L.et al, Indian Journal of Pharmaceutical Sciences ,2017
- Inhibitory Effects of Total Saponin Korean Red Ginseng on Thromboxane A Jung-Hae Shin.et al, The Korean Society For Biomedical Laboratory Sciences,2017
- Inhibitory effects of thromboxane A2 generation by ginsenoside Ro due to attenuation of cytosolic phospholipase A2 phosphorylation Jung-Hae Shin.et al,Journal of Ginseng Research,2018
- Surfactant Protein B Suppresses Lung Cancer Progression by Inhibiting Secretory Phospholipase A2 Activity and Arachidonic Acid Production Lee S.et al,Cell Physiol Biochem,2017
- Antipsychotic Drugs Inhibit Platelet Aggregation via P2Y1 and P2Y12 Receptors Chang-Chieh Wu.et al,BioMed Research International,2016
- H-rev107 Regulates Cytochrome P450 Reductase Activity and Increases Lipid Accumulation Tsai FM. et al,PLoS One,2015
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相關(guān)產(chǎn)品
靶點(diǎn)詳情
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最新研究進(jìn)展：近年來(lái)，花生四烯酸（Arachidonic Acid，AA）的研究重點(diǎn)主要集中在其與疾病的關(guān)系、作用機(jī)制以及調(diào)節(jié)方法等方面。一些研究表明，花生四烯酸的代謝異常與多種疾病密切相關(guān)。例如，心血管疾病的發(fā)生與發(fā)展與花生四烯酸的代謝異常有關(guān)，AA通過(guò)氧化代謝生成的炎癥介質(zhì)，如前列腺素和白三烯等，可導(dǎo)致血管內(nèi)皮損傷、炎癥反應(yīng)和血栓形成等。同時(shí)，花生四烯酸在腫瘤發(fā)生和發(fā)展中也發(fā)揮了一定的作用?；ㄉ南┧岽x產(chǎn)物可以促進(jìn)腫瘤細(xì)胞增殖、侵襲和轉(zhuǎn)移，并在腫瘤的血管生成過(guò)程中發(fā)揮一定的作用。研究人員可通過(guò)調(diào)節(jié)花生四烯酸的代謝途徑，探索其在疾病預(yù)防和治療方面的作用機(jī)制。例如，一些研究表明，通過(guò)調(diào)節(jié)花生四烯酸代謝途徑，可以降低炎癥介質(zhì)的生成，從而減輕炎癥反應(yīng)，預(yù)防和治療炎癥性疾病。此外，還有一些研究試圖通過(guò)抑制花生四烯酸代謝途徑，阻止腫瘤細(xì)胞的生長(zhǎng)和擴(kuò)散，具有一定的潛在治療價(jià)值。
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