Human 4-Hydroxynonenal (HNE)ELISA Kit

Human 4-Hydroxynonenal (HNE)ELISA Kit

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中文名稱：

人4-羥基壬烯酸(HNE)酶聯(lián)免疫試劑盒
貨號：

CSB-E16214h
規(guī)格：

96T/48T
價格：

￥3600/￥2500
促銷：
其他：

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產(chǎn)品描述：

人4-羥基壬烯酸(HNE)酶聯(lián)免疫試劑盒（CSB-E16214h）為競爭法ELISA試劑盒，定量檢測血清、血漿、組織勻漿樣本中的HNE含量。人中性粒細(xì)胞彈性蛋白酶（HNE）是一種絲氨酸蛋白酶，存在于中性粒細(xì)胞嗜天青顆粒中。HNE與多種疾病如肺氣腫、囊性纖維化等密切相關(guān)。研究機(jī)制主要圍繞抑制其活性來開發(fā)藥物，以減輕因HNE過度表達(dá)引發(fā)的炎癥和組織損傷。試劑盒檢測范圍為39 pg/mL-2500 pg/mL，適用于基礎(chǔ)科研中氧化應(yīng)激相關(guān)疾病模型的機(jī)制研究、藥物或天然產(chǎn)物的抗氧化功效評價，以及代謝組學(xué)中脂質(zhì)過氧化程度的動態(tài)監(jiān)測，為探索HNE在生理病理過程中的調(diào)控作用提供可靠工具。本品僅用于科研，不用于臨床診斷，產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
縮寫：

HNE
種屬：

Homo sapiens (Human)
樣本類型：

serum, plasma, tissue homogenates
檢測范圍：

39 pg/mL-2500 pg/mL
靈敏度：

19.5 pg/mL
反應(yīng)時間：

1-5h
樣本體積：

50-100ul
檢測波長：

450 nm
研究領(lǐng)域：

Signal Transduction
測定原理：

quantitative
測定方法：

Competitive

精密度：

線性度：

To assess the linearity of the assay, samples were spiked with high concentrations of human HNE in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.

	Sample	Serum(n=4)
1:100	Average %	89
	Range %	82-96
1:200	Average %	90
	Range %	85-96
1:400	Average %	85
	Range %	81-92
1:800	Average %	98
	Range %	91-104

回收率：

標(biāo)準(zhǔn)曲線：

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

pg/ml

OD1

OD2

Average

2500

0.175

0.170

0.173

1250

0.261

0.273

0.267

625

0.383

0.408

0.396

312.5

0.669

0.629

0.649

156.25

1.008

1.021

1.014

1.345

1.353

1.349

1.879

1.784

1.832

2.611

2.525

2.568

數(shù)據(jù)處理：

ELISA操作視頻及標(biāo)曲繪制軟件下載
貨期：

3-5 working days

The umbilical cord blood exosome MFG-E8 alleviates hypoxic-ischemic encephalopathy brain injury in neonatal rats by restoring autophagy flux and inhibiting ferroptosis through GSK3β/β-catenin signaling M Zhao, Y Wu, L Huang, J Wang, A Zhang,Regenerative Therapy,2025
Insulin Resistance and 4-Hydroxynonenal in Obesity-Associated Lipid Peroxidation of Adipocytes: A Comparative Cross-Sectional Study S Ramsridhar, C Rajkumar, PN Adtani,Journal of International Dental and Medical Research,2024
Treatment of human sperm with GYY4137 increases sperm motility and resistance to oxidative stress Y Huang, R Gan, M Zhang, D Lin, Y Cheng, X Guo,Zygote,2024
A Randomised, Double-Blind, Placebo-Controlled, Cross-Over Clinical Trial to Evaluate the Biological Effects and Safety of a Polyphenol Supplement on Healthy Ageing JR Chong, C de Lucia, DA Tovar-Rios,Antioxidants,2024
COPZ1 regulates ferroptosis through NCOA4-mediated ferritinophagy in lung adenocarcinoma A Wu,/,2023
Genome-Wide Screening Identifies Gene AKR1C1 Critical for Resistance to Pirarubicin in Bladder Cancer Z Nie,Cancers,2023
The Influence of Winter Swimming on Oxidative Stress Indicators in the Blood of Healthy Males R Weso?owski,Metabolites,2023
Serum Level of 4-Hydroxynonenal in Community-Acquired Pneumonia: A Potential Biomarker for Severity and Prognosis L Fu,Frontiers in Medicine,2022
Do different lipid components accelerate the pathogenesis and severity of Diabetic Retinopathy? Lakshmi Kanta Mondal,International Journal of Retina and Vitreous,2022
Sunitinib and Pterostilbene Combination Treatment Exerts Antitumor Effects in Gastric Cancer via Suppression of PDZD8 Y Hojo,International journal of molecular sciences,2022
Role of Lipid, Protein-Derived Toxic Molecules, and Deficiency of Antioxidants behind the Pathogenesis of Diabetic Retinopathy (DR) in Type 2 Diabetes Mellitus S Pramanik,/,2021
Oxidative stress in lung cancer patients is associated with altered serum markers of lipid metabolism Zablocka-Slowinska K, et al,PLoS One,2019
Asociación del hydroxynonenal 4 con las adipoquinas clásicas y la resistencia a la insulina en una población china obesa no diabética Guo, Lin.et al,Nutrici貿(mào)n Hospitalaria,2016
Melatonin Supplementation Lowers Oxidative Stress and Regulates Adipokines in Obese Patients on a Calorie-Restricted Diet Karolina Szewczyk-Golec.et al,Oxidative Medicine and Cellular Longevity,2017
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4-hydroxynonenal causes impairment of human subcutaneous adipogenesis and induction of adipocyte insulin resistance Mohamed Elrayess.et al,Free Radical Biology and Medicine,2017
4-Hydroxynonenal Regulates TNF-α Gene Transcription Indirectly via ETS1 and microRNA-29b in Human Adipocytes Induced From Adipose Tissue-Derived Stromal Cells. Zhang XM.et al,Anat Rec (Hoboken).,2016
Oxidized Docosahexaenoic Acid Species and Lipid Peroxidation Products Increase Amyloidogenic Amyloid Precursor Protein Processing Grimm MO. et al,Neurodegener Dis,2015
Naturally occurring variation in the glutathione-S-transferase 4 gene determines neurodegeneration after traumatic brain injury /,Antioxidants & Redox Signaling,2013

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Intra-assay Precision (Precision within an assay): CV%<8%

Three samples of known concentration were tested twenty times on one plate to assess.

Inter-assay Precision (Precision between assays): CV%<10%

Three samples of known concentration were tested in twenty assays to assess.