WEE1
Wee1-like protein kinase is a protein in humans that is encoded by WEE1 gene. Acts as a negative regulator of entry into mitosis (G2 to M transition) by protecting the nucleus from cytoplasmically activated cyclin B1-complexed CDK1 before the onset of mitosis by mediating phosphorylation of CDK1 on 'Tyr-15'. Specifically phosphorylates and inactivates cyclin B1-complexed CDK1 reaching a maximum during G2 phase and a minimum as cells enter M phase. Phosphorylation of cyclin B1-CDK1 occurs exclusively on 'Tyr-15' and phosphorylation of monomeric CDK1 does not occur. Its activity increases during S and G2 phases and decreases at M phase when it is hyperphosphorylated. A correlated decrease in protein level occurs at M/G1 phase, probably due to its degradation.
WEE1 Antibodies
WEE1 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 種屬反應(yīng)性 | 應(yīng)用類(lèi)型 |
|---|---|---|---|
| CSB-PA062918 | Phospho-WEE1 (Ser642) Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA060083 | Phospho-WEE1 (S642) Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA060084 | Phospho-WEE1 (S53) Antibody | Human,Mouse,Rat | IHC, ELISA |
| CSB-PA060085 | WEE1 Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA16059A0Rb | WEE1 Antibody | Human | ELISA |
| CSB-PA16059B0Rb | WEE1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA16059C0Rb | WEE1 Antibody, FITC conjugated | Human | |
| CSB-PA16059D0Rb | WEE1 Antibody, Biotin conjugated | Human | ELISA |
WEE1 Proteins
WEE1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP026084HU CSB-BP026084HU CSB-MP026084HU CSB-EP026084HU-B |
Recombinant Human Wee1-like protein kinase (WEE1) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP026084HU | Recombinant Human Wee1-like protein kinase (WEE1) | E.coli |
| CSB-EP026084HUc7 | Recombinant Human Wee1-like protein kinase (WEE1) | E.coli |
WEE1 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP026084MO CSB-BP026084MO CSB-MP026084MO CSB-EP026084MO-B |
Recombinant Mouse Wee1-like protein kinase (Wee1) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
WEE1 Proteins for Drosophila melanogaster (Fruit fly)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP026084DLU CSB-EP026084DLU CSB-BP026084DLU CSB-MP026084DLU CSB-EP026084DLU-B |
Recombinant Drosophila melanogaster Wee1-like protein kinase (wee) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
WEE1 Proteins for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP357135SXV CSB-EP357135SXV CSB-BP357135SXV CSB-MP357135SXV CSB-EP357135SXV-B |
Recombinant Schizosaccharomyces pombe Mitosis inhibitor protein kinase wee1 (wee1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
WEE1 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP723610RA CSB-EP723610RA CSB-BP723610RA CSB-MP723610RA CSB-EP723610RA-B |
Recombinant Rat Wee1-like protein kinase (Wee1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
WEE1 Proteins for Oryza sativa subsp. japonica (Rice)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP751135OFG CSB-EP751135OFG CSB-BP751135OFG CSB-MP751135OFG CSB-EP751135OFG-B |
Recombinant Oryza sativa subsp. japonica Wee1-like protein kinase (WEE1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
WEE1 Proteins for Arabidopsis thaliana (Mouse-ear cress)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP811852DOA CSB-EP811852DOA CSB-BP811852DOA CSB-MP811852DOA CSB-EP811852DOA-B |
Recombinant Arabidopsis thaliana Wee1-like protein kinase (WEE1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
