VPS11
VPS11 is a protein in humans that is encoded by VPS11 gene. Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes which are proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The HOPS complex is proposed to be recruited to Rab7 on the late endosomal membrane and to regulate late endocytic, phagocytic and autophagic traffic towards lysosomes. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations. Required for fusion of endosomes and autophagosomes with lysosomes. Involved in cargo transport from early to late endosomes and required for the transition from early to late endosomes. Involved in the retrograde Shiga toxin transport.
VPS11 Antibodies
VPS11 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA025889GA01HU | VPS11 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA887959ESR1HU | VPS11 Antibody | Human | ELISA, IHC |
| CSB-PA887959ESR2HU | VPS11 Antibody | Human | ELISA, IHC |
VPS11 Proteins
VPS11 Proteins for Dictyostelium discoideum (Slime mold)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP709890DKK CSB-EP709890DKK CSB-BP709890DKK CSB-MP709890DKK CSB-EP709890DKK-B |
Recombinant Dictyostelium discoideum Vacuolar protein sorting-associated protein 11 homolog (vps11), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
VPS11 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP845982MO CSB-EP845982MO CSB-BP845982MO CSB-MP845982MO CSB-EP845982MO-B |
Recombinant Mouse Vacuolar protein sorting-associated protein 11 homolog (Vps11), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
VPS11 Proteins for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP879105SXV CSB-EP879105SXV CSB-BP879105SXV CSB-MP879105SXV CSB-EP879105SXV-B |
Recombinant Schizosaccharomyces pombe Vacuolar membrane protein pep5 (pep5), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
VPS11 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP887959HU CSB-EP887959HU CSB-BP887959HU CSB-MP887959HU CSB-EP887959HU-B |
Recombinant Human Vacuolar protein sorting-associated protein 11 homolog (VPS11), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
