UBE3A
Ubiquitin-protein ligase E3A is a protein in humans that is encoded by UBE3A gene. E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. Several substrates have been identified including the RAD23A and RAD23B, MCM7 (which is involved in DNA replication), annexin A1, the PML tumor suppressor, and the cell cycle regulator CDKN1B. Catalyzes the high-risk human papilloma virus E6-mediated ubiquitination of p53/TP53, contributing to the neoplastic progression of cells infected by these viruses. Additionally, may function as a cellular quality control ubiquitin ligase by helping the degradation of the cytoplasmic misfolded proteins. Finally, UBE3A also promotes its own degradation in vivo. Plays an important role in the regulation of the circadian clock
UBE3A Antibodies
UBE3A for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA025488GA01HU | UBE3A Antibody | Human,Mouse,Rat | ELISA,WB,IF |
| CSB-PA025488LA01HU | UBE3A Antibody | Human | ELISA, IHC, IF |
| CSB-PA025488LB01HU | UBE3A Antibody, HRP conjugated | Human | ELISA |
| CSB-PA025488LC01HU | UBE3A Antibody, FITC conjugated | Human | |
| CSB-PA025488LD01HU | UBE3A Antibody, Biotin conjugated | Human | ELISA |
UBE3A Proteins
UBE3A Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP025488MO | Recombinant Mouse Ubiquitin-protein ligase E3A (Ube3a), partial | Yeast |
| CSB-MP025488MO | Recombinant Mouse Ubiquitin-protein ligase E3A (Ube3a), partial | Mammalian cell |
| CSB-EP025488MO | Recombinant Mouse Ubiquitin-protein ligase E3A (Ube3a), partial | E.coli |
| CSB-BP025488MO CSB-EP025488MO-B |
Recombinant Mouse Ubiquitin-protein ligase E3A (Ube3a), partial | Baculovirus In Vivo Biotinylation in E.coli |
