TYR
酪氨酸酶（TYR）是黑色素合成的核心催化劑，又稱多酚氧化酶，廣泛存在于皮膚、毛發等組織的黑色素細胞中。它通過促使酪氨酸轉化為多巴醌，推動黑色素顆粒的形成，直接影響生物體膚色與紫外線防護能力。該蛋白活性異常與多種疾病密切相關：先天性TYR功能缺陷會導致眼皮膚白化病，患者表現為皮膚、毛發色素缺失及視力障礙；而TYR過度激活則與惡性黑色素瘤、黃褐斑等色素沉著性疾病相關。近年來，針對TYR的抑制劑成為化妝品和皮膚病藥物研發熱點，熊果苷、曲酸等天然成分已應用于美白產品，新型小分子化合物如硫脲衍生物、金屬螯合劑等進入臨床試驗階段。值得一提的是，部分抗癌藥物通過調控TYR表達來抑制黑色素瘤轉移，而基于蛋白結構的靶向藥物設計也為治療遺傳性白化病提供了新思路。當前研究不僅關注TYR的催化功能，還探索其在神經保護、免疫調節中的潛在作用，這為跨疾病領域的治療策略開辟了新方向。
熱銷產品
Recombinant Human Tyrosinase (TYR), partial (CSB-YP025394HU)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
TYR Recombinant Monoclonal Antibody (CSB-RA567167A0HU)
驗證數據
Immunofluorescence staining of MCF7 Cells with CSB-RA567167A0HU at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeated by 0.2% TritonX-100, and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4℃. Nuclear DNA was labeled in blue with DAPI. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L).
Human Tyrosinase(TYR) ELISA kit (CSB-EL025394HU)
驗證數據
貨號：CSB-EL025394HU
規格：96T/48T
靈敏度：3.9 pg/mL
檢測范圍：15.6 pg/mL-1000 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
TYR Antibodies
TYR for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA025394LA01HU | TYR Antibody | Human | ELISA, IHC, IF |
| CSB-PA025394LB01HU | TYR Antibody, HRP conjugated | Human | ELISA |
| CSB-PA025394LC01HU | TYR Antibody, FITC conjugated | Human | |
| CSB-PA025394LD01HU | TYR Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA589649 | Tyrosinase Antibody | Human | WB |
| CSB-PA004353 | TYR Antibody | Human,Monkey | WB, ELISA |
| CSB-PA112776 | TYR Antibody | Human,Mouse | ELISA,WB |
| CSB-PA986893 | TYR Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-RA567167A0HU | TYR Recombinant Monoclonal Antibody | Human | ELISA, IF |
TYR Proteins
TYR Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP025394MO1 CSB-EP025394MO1 CSB-BP025394MO1 CSB-MP025394MO1 CSB-EP025394MO1-B |
Recombinant Mouse Tyrosinase (Tyr), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF025394MO | Recombinant Mouse Tyrosinase (Tyr) | in vitro E.coli expression system |
TYR Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP025394HU | Recombinant Human Tyrosinase (TYR), partial | Yeast |
| CSB-EP025394HU | Recombinant Human Tyrosinase (TYR), partial | E.coli |
| CSB-BP025394HU CSB-MP025394HU CSB-EP025394HU-B |
Recombinant Human Tyrosinase (TYR), partial | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-BP025394HU2 | Recombinant Human Tyrosinase (TYR), partial | Baculovirus |
TYR Proteins for Gallus gallus (Chicken)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP025394CH1 CSB-EP025394CH1 CSB-BP025394CH1 CSB-MP025394CH1 CSB-EP025394CH1-B |
Recombinant Chicken Tyrosinase (TYR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF025394CH | Recombinant Chicken Tyrosinase (TYR) | in vitro E.coli expression system |
TYR Proteins for Canis familiaris (Dog) (Canis lupus familiaris)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP025394DO1 CSB-EP025394DO1 CSB-BP025394DO1 CSB-MP025394DO1 CSB-EP025394DO1-B |
Recombinant Dog Tyrosinase (TYR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF025394DO | Recombinant Dog Tyrosinase (TYR) | in vitro E.coli expression system |
TYR Proteins for Felis catus (Cat) (Felis silvestris catus)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP025394CA CSB-EP025394CA CSB-BP025394CA CSB-MP025394CA CSB-EP025394CA-B |
Recombinant Cat Tyrosinase (TYR) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TYR Proteins for Pelophylax nigromaculatus (Black-spotted frog) (Rana nigromaculata)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP025394PEM1 CSB-EP025394PEM1 CSB-BP025394PEM1 CSB-MP025394PEM1 CSB-EP025394PEM1-B |
Recombinant Pelophylax nigromaculatus Tyrosinase (TYR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF025394PEM | Recombinant Pelophylax nigromaculatus Tyrosinase (TYR) | in vitro E.coli expression system |
TYR Proteins for Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP025394PEL CSB-EP025394PEL CSB-BP025394PEL CSB-MP025394PEL CSB-EP025394PEL-B |
Recombinant Pelodiscus sinensis Tyrosinase (TYR) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TYR Proteins for Oryzias latipes (Medaka fish) (Japanese ricefish)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP025394OFH1 CSB-EP025394OFH1 CSB-BP025394OFH1 CSB-MP025394OFH1 CSB-EP025394OFH1-B |
Recombinant Oryzias latipes Tyrosinase (tyr), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF025394OFH | Recombinant Oryzias latipes Tyrosinase (tyr) | in vitro E.coli expression system |
TYR Proteins for Coturnix coturnix japonica (Japanese quail) (Coturnix japonica)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP600102DXJ CSB-EP600102DXJ CSB-BP600102DXJ CSB-MP600102DXJ CSB-EP600102DXJ-B |
Recombinant Coturnix coturnix japonica Tyrosinase (TYR) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TYR Proteins for Bos taurus (Bovine)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP818647BO CSB-EP818647BO CSB-BP818647BO CSB-MP818647BO CSB-EP818647BO-B |
Recombinant Bovine Tyrosinase (TYR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TYR Proteins for Gorilla gorilla gorilla (Lowland gorilla)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP860196GGZ CSB-EP860196GGZ CSB-BP860196GGZ CSB-MP860196GGZ CSB-EP860196GGZ-B |
Recombinant Gorilla gorilla gorilla Tyrosinase (TYR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TYR ELISA Kit
TYR ELISA Kit for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL025394HU | Human Tyrosinase(TYR) ELISA kit | serum, plasma, tissue homogenates | 3.9 pg/mL |
TYR ELISA Kit for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL025394MO | Mouse Tyrosinase(TYR) ELISA kit | serum, plasma, tissue homogenates, cell lysates | 7.8 pg/mL |
