TRAM1
TRAM1，即易位相關膜蛋白1，別名TRAM、PNAS8、TRAMP。這是一種在人類細胞內質網中表達的多通道膜蛋白。TRAM1的作用機制涉及影響糖基化，并在新生多肽鏈的易位暫停期間，通過調節哪些結構域對胞質溶膠可見，來促進分泌蛋白跨內質網膜的易位。它還可能影響SEC61通道附近的磷脂雙層，從而促進蛋白質的內質網運輸，并在內質網應激條件下，參與未折疊蛋白反應（UPR）中的蛋白質降解過程。TRAM1在多種生物學過程中發揮作用，包括宿主-病毒相互作用、蛋白質運輸、易位和未折疊蛋白反應。異常的TRAM1表達與多種疾病相關，如Meckel綜合征2型、Oropouche熱、神經細胞脂褐質沉積癥8型Northern癲癇變體、Varadi-Papp綜合征等。
熱銷產品
Recombinant Human Translocating chain-associated membrane protein 1 (TRAM1), partial
CSB-YP618990HU
來源：Yeast
CSB-EP618990HU
來源：E.coli
CSB-BP618990HU
來源：Baculovirus
CSB-MP618990HU
來源：Mammalian cell
CSB-EP618990HU-B
來源：In Vivo Biotinylation in E.coli
TRAM1 Antibodies
TRAM1 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA024221GA01HU | TRAM1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
TRAM1 Proteins
TRAM1 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP618990HU CSB-EP618990HU CSB-BP618990HU CSB-MP618990HU CSB-EP618990HU-B |
Recombinant Human Translocating chain-associated membrane protein 1 (TRAM1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TRAM1 Proteins for Pongo abelii (Sumatran orangutan)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP719168PYX CSB-EP719168PYX CSB-BP719168PYX CSB-MP719168PYX CSB-EP719168PYX-B |
Recombinant Pongo abelii Translocating chain-associated membrane protein 1 (TRAM1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TRAM1 Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP723043RA CSB-EP723043RA CSB-BP723043RA CSB-MP723043RA CSB-EP723043RA-B |
Recombinant Rat Translocating chain-associated membrane protein 1 (Tram1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TRAM1 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP852767MO CSB-EP852767MO CSB-BP852767MO CSB-MP852767MO CSB-EP852767MO-B |
Recombinant Mouse Translocating chain-associated membrane protein 1 (Tram1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TRAM1 Proteins for Bos taurus (Bovine)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP875599BO CSB-EP875599BO CSB-BP875599BO CSB-MP875599BO CSB-EP875599BO-B |
Recombinant Bovine Translocating chain-associated membrane protein 1 (TRAM1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
